DALARGIN

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C35H51N9O8
Molecular Weight	725.8349
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)CC2=CC=C(O)C=C2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI

InChIKey=GDPHPXYFLPDZGH-XBTMSFKCSA-N

InChI=1S/C35H51N9O8/c1-20(2)16-27(32(49)43-26(34(51)52)10-7-15-39-35(37)38)44-33(50)28(18-22-8-5-4-6-9-22)42-29(46)19-40-30(47)21(3)41-31(48)25(36)17-23-11-13-24(45)14-12-23/h4-6,8-9,11-14,20-21,25-28,45H,7,10,15-19,36H2,1-3H3,(H,40,47)(H,41,48)(H,42,46)(H,43,49)(H,44,50)(H,51,52)(H4,37,38,39)/t21-,25+,26+,27+,28+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C35H51N9O8
Molecular Weight	725.8349
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Opioid receptors; mu/kappa/delta 33 Target ID: CHEMBL2095181 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2416590	Agonist 2752

PubMed

Title	Date	PubMed
Nephroprotective effect of GSK-3β inhibition by lithium ions and δ-opioid receptor agonist dalargin on gentamicin-induced nephrotoxicity.	2013-07-18	23651617

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:51:38 GMT 2025` Edited by `admin` on `Mon Mar 31 19:51:38 GMT 2025`
Record UNII	V13505565P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-6-(D-ALA2)-DYNORPHIN

Preferred Name

English

DALARGIN

Common Name

English

1-6-.BETA.-NEOENDORPHIN (HUMAN), 2-D-ALANINE-

Common Name

English

Dalargin [WHO-DD]

Common Name

English

L-ARGININE, L-TYROSYL-D-ALANYLGLYCYL-L-PHENYLALANYL-L-LEUCYL-

Common Name

English

DALARGINE

Common Name

English

Code System Code Type Description

CAS

81733-79-1