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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H28O6
Molecular Weight 292.3685
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CAPRYLYL GLUCOSIDE

SMILES

CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI

InChIKey=HEGSGKPQLMEBJL-RKQHYHRCSA-N
InChI=1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

HIDE SMILES / InChI

Molecular Formula C14H28O6
Molecular Weight 292.3685
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

CAPRYLYL GLUCOSIDE is a mild and non-denaturing detergent for the solubilization and reconsititution of membrane bound proteins. Treatment with 1.2% N-octylglucoside for 5 min completely inhibited HIV-1 infectivity. CAPRYLYL GLUCOSIDE being nontoxic and inexpensive agent in inhibiting Staphylococcus epidermidis and Pseudomonas aeruginosa adhesion to conventional and silicone-hydrogel contact lenses. CAPRYLYL GLUCOSIDE was tested for the treatment of pulmonary tuberculosis. It was shown, that surfactant is proficient in removing Mycobacterium tuberculosis shield. Thus, it may also enhance the effectiveness of antibiotics and the immune system's response in the treatment of pulmonary tuberculosis.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Mice: 25 ul of surfactant in 0.15M NaCl was administered utilizing a Penn-Century syringe and shaft. Two days in succession weekly for three weeks and once in the fourth week.
Route of Administration: Other
In Vitro Use Guide
Treatment with 1.2% N-octylglucoside for 5 min completely inhibited HIV-1 infectivity.
Substance Class Chemical
Record UNII
V109WUT6RL
Record Status Validated (UNII)
Record Version