FLORANTYRONE

First approved in 1957

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H14O3
Molecular Weight	302.3234
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CCC(=O)C1=CC2=C(C=C1)C3=CC=CC4=C3C2=CC=C4

InChI

InChIKey=QOBAOSCOLAGPKI-UHFFFAOYSA-N

InChI=1S/C20H14O3/c21-18(9-10-19(22)23)13-7-8-14-15-5-1-3-12-4-2-6-16(20(12)15)17(14)11-13/h1-8,11H,9-10H2,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C20H14O3
Molecular Weight	302.3234
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/10617 | https://www.ncbi.nlm.nih.gov/pubmed/13630699

FLORANTYRONE is a drug used in the treatment of biliary dyskinesia.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
biliary dyskinesia 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13630699	Primary		Approved 8429	Zanchol Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY558077	https://www.001chemical.com/chem/519-95-9
ABI Chem	AC1L1VL4
AN PharmaTech	AN-45513
Ambinter	Amb22731972	http://www.ambinter.com/reference/22731972
BOC Sciences	519-95-9
ChemMol	49427608	http://www.chemmol.com/chemmol/49427608.html
ChemMol	99099137	http://www.chemmol.com/chemmol/99099137.html
Chemieliva Pharmaceutical Co., Ltd	PBCM0614073
Molcore	MC558077	https://www.molcore.com/product/519-95-9
NovoSeek	10617
OChem	12431	http://www.ocheminc.com/index.php?act=psearch&pid=519F959
Smolecule	S528082	http://www.smolecule.com/products/s528082
THE BioTek	bt-268186	https://www.thebiotek.com/product/inhibitors/bt-268186
ZINC	ZINC000002036732	http://zinc15.docking.org/substances/ZINC000002036732

PubMed

Title	Date	PubMed
Effect of florantyrone on rate of secretion of hepatic bile and on its chemical and physical properties.	1959 Dec	13791630
Clinical impressions of a new hydrocholeretic agent, zanchol.	1959 Jan	13606110
Clinical study with a new hydrocholeretic drug and a new hydrocholeretic-antispasmodic combination.	1959 Mar	13630699

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:54:47 GMT 2023` Edited by `admin` on `Sat Dec 16 04:54:47 GMT 2023`
Record UNII	UZ5LMI200P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLORANTYRONE

Official Name

English

FLORANTYRONE [HSDB]

Common Name

English

.GAMMA.-OXO-8-FLUORANTHENEBUTYRIC ACID

Systematic Name

English

FLORANTYRONE [MI]

Common Name

English

Florantyrone [WHO-DD]

Common Name

English

florantyrone [INN]

Common Name

English

FLORANTYRONE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66913