2H-INDAZOLE-7-CARBOXYLIC ACID, 2-(4-(3S)-3-PIPERIDINYLPHENYL)-

OC(=O)C1=CC=CC2=CN(N=C12)C3=CC=C(C=C3)[C@@H]4CCCNC4

InChIKey=HDQHGRLURKGIFL-CQSZACIVSA-N

InChI=1S/C19H19N3O2/c23-19(24)17-5-1-3-15-12-22(21-18(15)17)16-8-6-13(7-9-16)14-4-2-10-20-11-14/h1,3,5-9,12,14,20H,2,4,10-11H2,(H,23,24)/t14-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
Poly [ADP-ribose] polymerase-1 23 Target ID: CHEMBL3105 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25761096	Inhibitor 8297		3.8 nM [IC50]

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Sat Dec 16 13:49:13 UTC 2023` Edited by `admin` on `Sat Dec 16 13:49:13 UTC 2023`
Record UNII	UXM824C9GS
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2H-INDAZOLE-7-CARBOXYLIC ACID, 2-(4-(3S)-3-PIPERIDINYLPHENYL)-

Systematic Name

English

NIRAPARIB METABOLITE M1

Common Name

English

Code System Code Type Description

FDA UNII

UXM824C9GS

Created by admin on Sat Dec 16 13:49:13 UTC 2023 , Edited by admin on Sat Dec 16 13:49:13 UTC 2023

PRIMARY

CAS

1476777-06-6

Created by admin on Sat Dec 16 13:49:13 UTC 2023 , Edited by admin on Sat Dec 16 13:49:13 UTC 2023

PRIMARY

PUBCHEM

118737587

Created by admin on Sat Dec 16 13:49:13 UTC 2023 , Edited by admin on Sat Dec 16 13:49:13 UTC 2023

PRIMARY

Related Record Type Details


					HMC2H89N35

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