PSEUDOPELLETIERINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15NO
Molecular Weight	153.2215
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1[C@H]2CCC[C@@H]1CC(=O)C2

InChI

InChIKey=RHWSKVCZXBAWLZ-OCAPTIKFSA-N

InChI=1S/C9H15NO/c1-10-7-3-2-4-8(10)6-9(11)5-7/h7-8H,2-6H2,1H3/t7-,8+

HIDE SMILES / InChI

Molecular Formula	C9H15NO
Molecular Weight	153.2215
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.creative-enzymes.com/product/pseudopelletierine_8782.html | http://rhodiolarosea.org/pomegranate.pdf

Pseudopelletierine is the main alkaloid derived from the root-bark of the pomegranate tree (Punica granatum). Pseudopelletierine is used as an enzyme substrate.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
amyloid beta-protein (1-40) 3 Target ID: amyloid beta-protein (1-40) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19715547	Binding Agent 1064

Conditions

Condition	Modality	Targets	Highest Phase	Product
Alzheimer’s disease 272 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19715547	Primary		Basic research	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Dolasetron overdose resulting in prolonged QTc interval and severe hypotension: a case report and literature review.	2007 Jul	17582056
Association constants of pyridine and piperidine alkaloids to amyloid beta peptide determined by electrochemical impedance spectroscopy.	2010 Mar	19715547

Patents

Sample Use Guides

In Vivo Use Guide

Guinea pig: LDLo - subcutaneous, 230 mg/kg

Route of Administration: Other

In Vitro Use Guide

Binding to Abeta(1-40) of pseudopelletierine was (0.57 x 10(8) M(-1)

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:07:19 GMT 2023` Edited by `admin` on `Sat Dec 16 10:07:19 GMT 2023`
Record UNII	USN3FV3Z9X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PSEUDOPELLETIERINE

Common Name

English

.OMEGA.-PELLETIERINE

Common Name

English

9-AZABICYCLO(3.3.1)NONAN-3-ONE, 9-METHYL-

Systematic Name

English

PSEUDOPUNICINE

Common Name

English

PSEUDOPELLETIERINE [MI]

Common Name

English

9-METHYL-3-GRANATANONE

Common Name

English

9-METHYL-9-AZABICYCLO(3.3.1)NONAN-3-ONE

Systematic Name

English

PSEUDOPELLETIERIN

Common Name

English

NSC-116056

Code

English

GRANATAN-3-ONE

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

209-021-1