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Details

Stereochemistry ACHIRAL
Molecular Formula C4H6O
Molecular Weight 70.0898
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-BUTYNOL

SMILES

CC#CCO

InChI

InChIKey=NEEDEQSZOUAJMU-UHFFFAOYSA-N
InChI=1S/C4H6O/c1-2-3-4-5/h5H,4H2,1H3

HIDE SMILES / InChI

Molecular Formula C4H6O
Molecular Weight 70.0898
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Platinum-catalyzed multi-step reaction of propargyl alcohols with N-heteroaromatics.
2010-01-04
Synthesis and activity of quinolinylmethyl P1' alpha-sulfone piperidine hydroxamate inhibitors of TACE.
2009-07-01
Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors.
2009-06-01
Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket.
2007-09-15
The use of silicon-based tethers for the Pauson-Khand reaction.
2007-07-06
(eta(5)-Cyclopentadienyl)(3-hydroxy-3-methylbut-1-ynyl-kappaC(1))(triphenylphosphine-kappaP)nickel(II): novel O-H...pi bonding in an organometallic molecule.
2007-07
Synthesis of the 5-phosphono-pent-2-en-1-yl nucleosides: a new class of antiviral acyclic nucleoside phosphonates.
2007-02-15
Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
2005-10-01
Synthesis and structure-activity relationships of 4-alkynyloxy phenyl sulfanyl, sulfinyl, and sulfonyl alkyl hydroxamates as tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase inhibitors.
2004-12-02
Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates.
2003-08-18
Dehydration reaction of hydroxyl substituted alkenes and alkynes on the Ru(2)S(2) complex.
2002-11-06
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.
2002-09-12
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 2: SAR of the acetylenic P1' group.
2002-04-22
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:46:14 GMT 2025
Edited
by admin
on Mon Mar 31 21:46:14 GMT 2025
Record UNII
US5293942K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-222371
Preferred Name English
2-BUTYNOL
Systematic Name English
2-BUTYN-1-OL
Systematic Name English
2-BUTYNYL ALCOHOL
Systematic Name English
1-HYDROXYBUT-2-YNE
Systematic Name English
Code System Code Type Description
PUBCHEM
12991
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY
ECHA (EC/EINECS)
212-113-4
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY
FDA UNII
US5293942K
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY
CAS
764-01-2
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY
EPA CompTox
DTXSID8022115
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY
NSC
222371
Created by admin on Mon Mar 31 21:46:14 GMT 2025 , Edited by admin on Mon Mar 31 21:46:14 GMT 2025
PRIMARY