TECHNETIUM TC-99M NITRIDOCADE

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C5H10NOS2.N.Tc
Molecular Weight	441.451
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	-5

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M NITRIDOCADE

Structure Search

SMILES

[N-3].[99Tc].CCON(CC)C([S-])=S.CCON(CC)C([S-])=S

InChI

InChIKey=YROSGSZGCWASMD-SGNQUONSSA-L

InChI=1S/2C5H11NOS2.N.Tc/c2*1-3-6(5(8)9)7-4-2;;/h2*3-4H2,1-2H3,(H,8,9);;/q;;-3;/p-2/i;;;1+1

HIDE SMILES / InChI

Molecular Formula	HN
Molecular Weight	15.0146
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.9063
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C5H11NOS2
Molecular Weight	165.277
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:37:51 GMT 2023` Edited by `admin` on `Fri Dec 15 15:37:51 GMT 2023`
Record UNII	UQ9G2F6I3H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECHNETIUM TC-99M NITRIDOCADE

Common Name

English

99MTCN-NOET

Code

English

technetium (⁹⁹mTc) nitridocade [INN]

Common Name

English

(SUP 99M)TCN-NOET

Common Name

English

TECHNETIUM-99TC, BIS(ETHOXYETHYLCARBAMODITHIOATO-.KAPPA.S,.KAPPA.S')NITRIDO-, (SP-5-21)-

Common Name

English

TECHNETIUM (99MTC) NITRIDOCADE

Official Name

English

TECHNETIUM TC 99M NITRIDOCADE [USAN]

Common Name

English

TECHNETIUM TC 99M NITRIDOCADE

Official Name

English

99M-TCN-NOET

Code

English

(SP-5-21)-BIS(ETHOXYETHYLCARBAMODITHIOATO-.KAPPA.S,.KAPPA.S')NITRIDO(99MTC)TECHNETIUM

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124