Lasrekibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:28:37 GMT 2025` Edited by `admin` on `Wed Apr 02 20:28:37 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED RAT
Sequence Type	COMPLETE
Record UNII	UP8FP5L8D6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Lasrekibart

Official Name

English

H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-23*02 (88.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (215) (11

Preferred Name

English

Immunoglobulin G1 [253-tyrosine,255-threonine,257-glutamic acid], anti-(human interleukin-5) (human-Rattus norvegicus monoclonal HRP00488 ?1-chain), disulfide with human-Rattus norvegicus monoclonal HRP00488 ?-chain, dimer

Common Name

English

lasrekibart [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens IL5 (interleukin 5, IL-5)], humanized monoclonal antibody (lasrekibart)

Common Name

English

Code System Code Type Description

INN

13500

Created by admin on Wed Apr 02 20:28:37 GMT 2025 , Edited by admin on Wed Apr 02 20:28:37 GMT 2025

PRIMARY

FDA UNII

UP8FP5L8D6

Created by admin on Wed Apr 02 20:28:37 GMT 2025 , Edited by admin on Wed Apr 02 20:28:37 GMT 2025

PRIMARY

CAS

3021525-26-5

Created by admin on Wed Apr 02 20:28:37 GMT 2025 , Edited by admin on Wed Apr 02 20:28:37 GMT 2025

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_368	2_426
2_262	2_322
2_221	4_214
2_145	2_201
2_22	2_96
1_368	1_426
1_262	1_322
1_230	2_230
1_227	2_227
1_221	3_214
1_145	1_201
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					9O1TT75I7L

INTERLEUKIN-5

TARGET->LIGAND

Amount:

Related Record Type Details


					UP8FP5L8D6

Lasrekibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL