MANNOMUSTINE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H22Cl2N2O4.2ClH
Molecular Weight	378.121
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.O[C@H](CNCCCl)[C@@H](O)[C@H](O)[C@H](O)CNCCCl

InChI

InChIKey=GBKLAYXZNQSPBS-XYSQQLOGSA-N

InChI=1S/C10H22Cl2N2O4.2ClH/c11-1-3-13-5-7(15)9(17)10(18)8(16)6-14-4-2-12;;/h7-10,13-18H,1-6H2;2*1H/t7-,8-,9-,10-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	C10H22Cl2N2O4
Molecular Weight	305.199
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13671231 | https://www.ncbi.nlm.nih.gov/pubmed/13910448 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about | https://www.drugfuture.com/chemdata/mannomustine.html

Mannomustine is a substance synthesized as one of a series of compounds linking the actively cytotoxic chemical group beta-chlorethylamine with a naturally occurring substance, mannitol. Mannomustine is an alkylating agent with antineoplastic properties. It was being studied in the treatment of hematologic malignancies.

Originator

Approval Year

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

the maximal single dose is 100 mg daily or on alternate days

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:58:57 GMT 2023` Edited by `admin` on `Sat Dec 16 10:58:57 GMT 2023`
Record UNII	UOZ2JJZ3I5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MANNOMUSTINE HYDROCHLORIDE

Common Name

English

MANNITOL MUSTARD DIHYDROCHLORIDE

Common Name

English

1,6-BIS(.BETA.-CHLORETHYLAMINO)-1,6-DIDESOXY-D-MANNITOL DIHYDROCHLORIDE

Systematic Name

English

MANNITOL, 1,6-BIS((2-CHLOROETHYL)AMINO)-1,6-DIDEOXY-, DIHYDROCHLORIDE, D-

Systematic Name

English

NSC-9698 HYDROCHLORIDE

Code

English

D-MANNITOL, 1,6-BIS((2-CHLOROETHYL)AMINO)-1,6-DIDEOXY-, DIHYDROCHLORIDE

Systematic Name

English

MANNOMUSTINE DIHYDROCHLORIDE [IARC]

Common Name

English

MANNOMUSTINE [MI]

Common Name

English

MANNOMUSTINE DIHYDROCHLORIDE

Common Name

English

DEGRANOL CHINOIN

Common Name

English

NSC-9698

Code

English

Code System Code Type Description

EPA CompTox

DTXSID40970470