Pegozafermin

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:58:56 GMT 2025` Edited by `admin` on `Tue Apr 01 22:58:56 GMT 2025`
Protein Type	GROWTH FACTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	UO870O6MFS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Pegozafermin

Official Name

English

FIBROBLAST GROWTH FACTOR 21 (METHIONYL,173-(O-(2-(ACETYLAMINO)-6-O-(N-(2-(CARBOXYAMINO)ACETYL)-.ALPHA.-NEURAMINOSYL)-2-DEOXY-.ALPHA.-D-GALACTOPYRANOSYL)THREONINE),176-ARGININE) (HUMAN CONSTRUCT BIO89-100), 173N-ESTER WITH .ALPHA.-HYDRO-.OMEGA.-METHOXYPOL

Preferred Name

English

TEV-47948

Code

English

BIO89-100 (LONG-ACTING GLYCOPEGYLATED FIBROBLAST GROWTH FACTOR 21 (FGF21) ANALOGUE)

Common Name

English

pegozafermin [INN]

Common Name

English

PEGOZAFERMIN [USAN]

Common Name

English

BIO89-100

Code

English

BIO89100

Code

English

Code System Code Type Description

CAS

2489589-60-6

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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FDA UNII

UO870O6MFS

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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SMS_ID

300000024036

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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NCI_THESAURUS

C188638

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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USAN

JK-214

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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INN

12406

Created by admin on Tue Apr 01 22:58:56 GMT 2025 , Edited by admin on Tue Apr 01 22:58:56 GMT 2025

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From	To
1_76	1_94

Glycosylation Type

Biosynthetic

Glycosylation Link Type	Site
O	1_173

Related Record Type Details


					YI71QO74DQ

FGF-21 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					UO870O6MFS

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_173]	SITE_SPECIFIC			UNSPECIFIED SUBSTANCE	bec33729 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL