U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C11H10N2S
Molecular Weight 202.276
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTU

SMILES

NC(=S)NC1=C2C=CC=CC2=CC=C1

InChI

InChIKey=PIVQQUNOTICCSA-UHFFFAOYSA-N
InChI=1S/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14)

HIDE SMILES / InChI

Molecular Formula C11H10N2S
Molecular Weight 202.276
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement.
2010-06
Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis.
2009-11-24
Characterization of and mechanism for copper-induced thioureation of serum albumin.
2008-09
Kinetics and determinants of the changes of CC16, a lung secretory protein in a rat model of toxic lung injury.
2008-03
Pulmonary endothelial cell signaling and function.
2008
Accumulation of oxidized low-density lipoprotein in psoriatic skin and changes of plasma lipid levels in psoriatic patients.
2007
Receptor for anionic pyrene derivatives provides the basis for new biomembrane assays.
2005-10-26
Wartime rat control, rodent ecology, and the rise and fall of chemical rodenticides.
2005-09
Development of time-resolved chemiluminescence for the determination of antu in river water, wheat, barley, and oat grain samples.
2005-08-24
Morphine modulates inducible nitric oxide synthase expression and reduces pulmonary oedema induced by alpha-naphthylthiourea.
2005-03-28
Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine.
2005-01-28
Oxidized low-density lipoproteins accumulate in rat lung after experimental lung edema induced by alpha- naphthylthiourea (ANTU).
2004-12
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
2004-05
Quantitation of pulmonary transgene expression with PET imaging.
2004-04
Granulocyte colony-stimulating factor enhances alpha-naphthylthiourea-induced pulmonary hypertension.
2003-05
Substituted heterocyclic thiourea compounds as a new class of anti-allergic agents inhibiting IgE/Fc epsilon RI receptor mediated mast cell leukotriene release.
2003-03-20
In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats.
2003-02
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase.
2003-01
Exacerbation by granulocyte colony-stimulating factor of prior acute lung injury: implication of neutrophils.
2002-09
Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3.
2002-06-01
Prevention of alpha-naphthylthiourea-induced pulmonary edema with fructose-1,6-diphosphate.
2002-06
Acute effects of pentobarbital, thiopental and urethane on lung oedema induced by alpha-naphthythiourea (ANTU).
2002-03
Significance of the changes in the respiratory system pressure-volume curve during acute lung injury in rats.
2001-08-15
Stereochemistry as a major determinant of the anti-HIV activity of chiral naphthyl thiourea compounds.
2001-07
Stimulated pulmonary cell hyperplasia underlies resistance to alpha-naphthylthiourea.
2000-02-21
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:46:17 GMT 2025
Edited
by admin
on Mon Mar 31 18:46:17 GMT 2025
Record UNII
UKY0H6XJ4J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTU
HSDB   ISO   MART.   MI  
Common Name English
ANTURAT
Preferred Name English
ANTU [MI]
Common Name English
NSC-3287
Code English
CHEMICAL 109
Common Name English
N-1-NAPHTHALENYLTHIOUREA
Systematic Name English
BANTU
Brand Name English
N-1-NAPHTHYLTHIOUREA
Systematic Name English
1-(1-NAPHTHYL)-2-THIOUREA
Systematic Name English
.ALPHA.-NAPHTHYLTHIOCARBAMIDE
Common Name English
.ALPHA.-NAPHTHYLTHIOUREA
Systematic Name English
ANTU [ISO]
Common Name English
KRYSID
Common Name English
NAPHTHYL)-2-THIOUREA, 1-(1-
Common Name English
ANTU [MART.]
Common Name English
RATTRACK
Brand Name English
ANTU [HSDB]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 4501
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
Code System Code Type Description
CAS
86-88-4
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
MESH
C005277
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
NSC
3287
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
HSDB
1512
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
ALANWOOD
antu
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
WIKIPEDIA
alpha-Naphthylthiourea
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
MERCK INDEX
m1978
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY Merck Index
PUBCHEM
736366
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-706-3
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
EPA CompTox
DTXSID8020919
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY
FDA UNII
UKY0H6XJ4J
Created by admin on Mon Mar 31 18:46:17 GMT 2025 , Edited by admin on Mon Mar 31 18:46:17 GMT 2025
PRIMARY