ANTU

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10N2S
Molecular Weight	202.276
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)NC1=C2C=CC=CC2=CC=C1

InChI

InChIKey=PIVQQUNOTICCSA-UHFFFAOYSA-N

InChI=1S/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C11H10N2S
Molecular Weight	202.276
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Stimulated pulmonary cell hyperplasia underlies resistance to alpha-naphthylthiourea.	2000 Feb 21	10755703
Significance of the changes in the respiratory system pressure-volume curve during acute lung injury in rats.	2001 Aug 15	11520727
Stereochemistry as a major determinant of the anti-HIV activity of chiral naphthyl thiourea compounds.	2001 Jul	11771730
Prevention of alpha-naphthylthiourea-induced pulmonary edema with fructose-1,6-diphosphate.	2002 Jun	12042031
Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3.	2002 Jun 1	12093470
Acute effects of pentobarbital, thiopental and urethane on lung oedema induced by alpha-naphthythiourea (ANTU).	2002 Mar	11884221
Exacerbation by granulocyte colony-stimulating factor of prior acute lung injury: implication of neutrophils.	2002 Sep	12352050
In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats.	2003 Feb	12527698
Sulphoxidation of ethyl methyl sulphide, 4-chlorophenyl methyl sulphide and diphenyl sulphide by purified pig liver flavin-containing monooxygenase.	2003 Jan	12519696
Substituted heterocyclic thiourea compounds as a new class of anti-allergic agents inhibiting IgE/Fc epsilon RI receptor mediated mast cell leukotriene release.	2003 Mar 20	12614897
Granulocyte colony-stimulating factor enhances alpha-naphthylthiourea-induced pulmonary hypertension.	2003 May	12524378
Quantitation of pulmonary transgene expression with PET imaging.	2004 Apr	15073262
Oxidized low-density lipoproteins accumulate in rat lung after experimental lung edema induced by alpha- naphthylthiourea (ANTU).	2004 Dec	15501696
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.	2004 May	15144220
Development of time-resolved chemiluminescence for the determination of antu in river water, wheat, barley, and oat grain samples.	2005 Aug 24	16104774
Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine.	2005 Jan 28	15642591
Morphine modulates inducible nitric oxide synthase expression and reduces pulmonary oedema induced by alpha-naphthylthiourea.	2005 Mar 28	15792787
Receptor for anionic pyrene derivatives provides the basis for new biomembrane assays.	2005 Oct 26	16231924
Wartime rat control, rodent ecology, and the rise and fall of chemical rodenticides.	2005 Sep	16087236
Accumulation of oxidized low-density lipoprotein in psoriatic skin and changes of plasma lipid levels in psoriatic patients.	2007	17497039
Pulmonary endothelial cell signaling and function.	2008	18596849
Kinetics and determinants of the changes of CC16, a lung secretory protein in a rat model of toxic lung injury.	2008 Mar	18344105
Characterization of and mechanism for copper-induced thioureation of serum albumin.	2008 Sep	18712897
Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis.	2009 Nov 24	19956603
Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement.	2010 Jun	20228181

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:25:34 GMT 2023` Edited by `admin` on `Fri Dec 15 17:25:34 GMT 2023`
Record UNII	UKY0H6XJ4J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANTU	Locators: HSDB ISO MART. MI Sources:

Common Name

English

ANTU [MI]

Common Name

English

NSC-3287

Code

English

CHEMICAL 109

Common Name

English

N-1-NAPHTHALENYLTHIOUREA

Systematic Name

English

BANTU

Brand Name

English

N-1-NAPHTHYLTHIOUREA

Systematic Name

English

1-(1-NAPHTHYL)-2-THIOUREA

Systematic Name

English

.ALPHA.-NAPHTHYLTHIOCARBAMIDE

Common Name

English

.ALPHA.-NAPHTHYLTHIOUREA

Systematic Name

English

ANTU [ISO]

Common Name

English

KRYSID

Common Name

English

ANTURAT

Brand Name

English

NAPHTHYL)-2-THIOUREA, 1-(1-

Common Name

English

ANTU [MART.]

Common Name

English

RATTRACK

Brand Name

English

ANTU [HSDB]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

4501