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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H22N2O6
Molecular Weight 386.3985
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Osivelotor

SMILES

OCCC1=C(C=CC=N1)C(=O)N2CCOC[C@H]2COC3=C(C=O)C(O)=CC=C3

InChI

InChIKey=NIWBSQAKKNNWBT-AWEZNQCLSA-N
InChI=1S/C20H22N2O6/c23-9-6-17-15(3-2-7-21-17)20(26)22-8-10-27-12-14(22)13-28-19-5-1-4-18(25)16(19)11-24/h1-5,7,11,14,23,25H,6,8-10,12-13H2/t14-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H22N2O6
Molecular Weight 386.3985
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 17:53:38 GMT 2023
Edited
by admin
on Sat Dec 16 17:53:38 GMT 2023
Record UNII
UK749B4S16
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Osivelotor
INN  
Official Name English
2-hydroxy-6-{[(3S)-4-{[2-(2-hydroxyethyl)pyridin-3- yl]carbonyl}morpholin-3-yl]methoxy}benzaldehyde
Systematic Name English
osivelotor [INN]
Common Name English
GBT-601
Code English
GBT-021601
Code English
2-hydroxy-6-{[(3S)-4-{[2-(2-hydroxyethyl)pyridin-3- yl]carbonyl}morpholin-3-yl]methoxy}benzaldehyde
Systematic Name English
GBT021601
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 877122
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
Code System Code Type Description
INN
12553
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
NCI_THESAURUS
C199086
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
PUBCHEM
146567655
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
CAS
2417955-18-9
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
SMS_ID
300000041190
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
FDA UNII
UK749B4S16
Created by admin on Sat Dec 16 17:53:38 GMT 2023 , Edited by admin on Sat Dec 16 17:53:38 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> ACTIVATOR
GBT021601 binds to HbS and increases its oxygen (O2) affinity, thereby stabilizing the oxygenated hemoglobin (oxyHb) state and inhibiting HbS polymerization
Related Record Type Details
ACTIVE MOIETY