2-HYDROXYPHENYLACETIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H8O3
Molecular Weight	152.1473
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC1=CC=CC=C1O

InChI

InChIKey=CCVYRRGZDBSHFU-UHFFFAOYSA-N

InChI=1S/C8H8O3/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4,9H,5H2,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C8H8O3
Molecular Weight	152.1473
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse.	2010-08-06	20540569
Vadimezan: 2-(5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid.	2010-07-21	21588382
Electrochemical incineration of diclofenac in neutral aqueous medium by anodic oxidation using Pt and boron-doped diamond anodes.	2010-04	20307900
catena-Poly[[[aqua-[(2-hydroxy-phen-yl)acetato-κO,O']lead(II)]-μ(3)-[(2-hydroxy-phen-yl)acetato-κO:O,O':O']] monohydrate].	2010-02-06	21580222
The kinetic effect of internal hydrogen bonds on proton-coupled electron transfer from phenols: a theoretical analysis with modeling of experimental data.	2009-12-17	20000384
The autocorrelation matrix probing biochemical relationships after metabolic fingerprinting with CE.	2009-04	19283696
Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production.	2009-02-10	19203396
Degradation of phenanthrene and anthracene by Nocardia otitidiscaviarum strain TSH1, a moderately thermophilic bacterium.	2008-08	18312570
The rate ladder of proton-coupled tyrosine oxidation in water: a systematic dependence on hydrogen bonds and protonation state.	2008-07-23	18582051
Characterisation of the substrate specificity of the nitrile hydrolyzing system of the acidotolerant black yeast Exophiala oligosperma R1.	2008	19287539
Near-ultraviolet photolysis of beta-phenylpyruvic acid generates free radicals and results in DNA damage.	2007-12-14	17977740
Dibutyl phthalate biodegradation by the white rot fungus, Polyporus brumalis.	2007-08-15	17221890
Isolation and characterization of a nitrile hydrolysing acidotolerant black yeast-Exophiala oligosperma R1.	2007-06	17361431
CprK crystal structures reveal mechanism for transcriptional control of halorespiration.	2006-09-22	16803881
Selected ectomycorrhizal fungi of black spruce (Picea mariana) can detoxify phenolic compounds of Kalmia angustifolia.	2006-07	16718563
[Isolation and characterization of a benzothiophene-desulfurizing bacterium].	2006-06	16921958
Isolation and characterization of a diverse group of phenylacetic acid degrading microorganisms from pristine soil.	2005-11	15869782
Synthesis of hydroxytyrosol, 2-hydroxyphenylacetic acid, and 3-hydroxyphenylacetic acid by differential conversion of tyrosol isomers using Serratia marcescens strain.	2005-08-10	16076144
Novel gamma-hydroxybutyric acid (GHB) analogs share some, but not all, of the behavioral effects of GHB and GABAB receptor agonists.	2005-06	15769868
Roles for epoxidation and detoxification of coumarin in determining species differences in clara cell toxicity.	2004-11	15282406
Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.	2004-08	15141102
Liquid chromatographic determination of the glutathione conjugate and ring-opened metabolites formed from coumarin epoxidation.	2003-09-05	12954377
Application of capillary electrophoresis with pH-mediated sample stacking to analysis of coumarin metabolites in microsomal incubations.	2003-08-08	12899967
Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli.	2003-07	12846838
Potential inhibitors of angiogenesis. Part II: 3-(azolylmethylene)-2,3-dihydrobenzo[b]furan-2-ones.	2003-06	14506916
Comparative metabolism and kinetics of coumarin in mice and rats.	2003-02	12480300
CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6.	2003-01	12519695
Biotransformation of N-(2-alkylamino-4-phenylimidazol-1-yl)-acetamides and kinetic studies by using cells and laccase from Trametes versicolor.	2003	14625901
Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats.	2002-12	12433803
Molecular analysis of aerobic phenylacetate degradation in Azoarcus evansii.	2002-07	12172805
Coumarin metabolism by rat esophageal microsomes and cytochrome P450 2A3.	2001-10	11599930
The in vivo dermal absorption and metabolism of [4-14C] coumarin by rats and by human volunteers under simulated conditions of use in fragrances.	2001-02	11267709
Determination of acidic metabolites of biogenic amines in human aqueous humour by gas chromatography--negative ion chemical ionisation mass spectrometry.	1992-01	1727423
Species differences in the metabolism and excretion of fenclofenac.	1980-10	7456491
Absence of a significant renal threshold for two aromatic acids in phenylketonuric children over two years of age.	1980-08	7439195
Phenylalanine metabolism in uremic and normal man.	1978-08	357810

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:58:49 GMT 2025` Edited by `admin` on `Mon Mar 31 19:58:49 GMT 2025`
Record UNII	UK3R9Q59AV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-HYDROXYPHENYLACETIC ACID

Systematic Name

English

NSC-62000

Preferred Name

English

BENZENEACETIC ACID, 2-HYDROXY-

Common Name

English

HYDROXYPHENYLACETIC ACID, O-

Common Name

English

(2-HYDROXYPHENYL)ACETIC ACID

Systematic Name

English

ACETIC ACID, (O-HYDROXYPHENYL)-

Common Name

English

(O-HYDROXYPHENYL)ACETIC ACID

Common Name

English

2-HYDROXYBENZENEACETIC ACID

Systematic Name

English

Code System Code Type Description

CHEBI

28478