Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C27H48O |
Molecular Weight | 388.6694 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI
InChIKey=QYIXCDOBOSTCEI-KKFSNPNRSA-N
InChI=1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20-,21-,22+,23-,24+,25+,26+,27-/m1/s1
Molecular Formula | C27H48O |
Molecular Weight | 388.6694 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Antilithiasic and hypocholesterolemic effects of diets containing autoclaved amylomaize starch in hamster. | 1995 Dec |
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Tracing sewage in the marine environment: altered signatures in Concepción Bay, Chile. | 2001 Dec |
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Short-term LDL cholesterol-lowering efficacy of plant stanol esters. | 2002 Aug 27 |
|
Indole alkaloids and other constituents of Rauwolfia serpentina. | 2005 Jun |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8866728
diabetic rats: epicoprostanol significantly induced hypoglycemia and increased insulin levels in rat blood plasma by 88% and 66% compared to that of control after 2 h and 4 h of acute treatment at 100 mg/kg dose.
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17408835
Ambrein and epicoprostanol were evaluated for their antioxidant potential in vitro by chemiluminescence (CL). Two low concentrations (5-20 microg/ml) of epicoprostanol inhibited CL significantly (P<0.001 and P<0.01, respectively) in comparison to DMSO control. The high concentration (40 microg/ml) of epicoprostanol behaved exceptionally and caused an increase in CL response that was more than control and significantly (P<0.001) higher than both the low concentrations.
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:42:39 GMT 2023
by
admin
on
Sat Dec 16 05:42:39 GMT 2023
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Record UNII |
UFH3K1F9EG
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Record Status |
Validated (UNII)
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Record Version |
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