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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H42O3
Molecular Weight 402.6099
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STANOLONE ENANTHATE

SMILES

[H][C@@]12CC[C@H](OC(=O)CCCCCC)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])CC(=O)CC[C@]34C

InChI

InChIKey=DDYHAKNCTGGYOK-LVYWIKMTSA-N
InChI=1S/C26H42O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h18,20-23H,4-17H2,1-3H3/t18-,20-,21-,22-,23-,25-,26-/m0/s1

HIDE SMILES / InChI

Molecular Formula C26H42O3
Molecular Weight 402.6099
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 7 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

STANOLONE, also known as dihydrotestosterone, is a potent androgenic metabolite of testosterone and anabolic agent for systemic use. It may be used as a replacement of male sex steroids in men who have androgen deficiency, for example as a result of the loss of both testes, and also the treatment of certain rare forms of aplastic anemia which are or may be responsive to anabolic androgens.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Neodrol

Cmax

ValueDoseCo-administeredAnalytePopulation
7.8 nM
16 mg single, topical
STANOLONE serum
Homo sapiens

AUC

ValueDoseCo-administeredAnalytePopulation
44.8 nM × h
16 mg single, topical
STANOLONE serum
Homo sapiens

T1/2

ValueDoseCo-administeredAnalytePopulation
12 day
16 mg single, topical
STANOLONE serum
Homo sapiens

Funbound

ValueDoseCo-administeredAnalytePopulation
2%
unknown, unknown
STANOLONE plasma
Homo sapiens

Doses

Drug as perpetrator​

Drug as victim

Tox targets

PubMed

Substance Class Chemical
Record UNII
UAQ3N36A25
Record Status Validated (UNII)
Record Version