ZAFTUCLENEGENE PIRUPARVOVEC TRANSGENE INSERT

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 18:42:46 GMT 2023` Edited by `admin` on `Sat Dec 16 18:42:46 GMT 2023`
Nucleic Acid Subtype
Record UNII	UA46HCC58W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZAFTUCLENEGENE PIRUPARVOVEC TRANSGENE INSERT

Common Name

English

ZAFTUCLENEGENE PIRUPARVOVEC TRANSGENE INSERT (CODON-OPTIMISED HUMAN PALMITOYL-PROTEIN THIOESTERASE 1 (PPT1, CLN1), UNDER THE CONTROL OF A SYNTHETIC PROMOTER CONSISTING OF A CYTOMEGALOVIRUS (CMV) ENHANCER/CHICKEN .BETA.-ACTIN (CBA) PROMOTER AND A HYBRID I

Common Name

English

Code System Code Type Description

FDA UNII

UA46HCC58W

Created by admin on Sat Dec 16 18:42:46 GMT 2023 , Edited by admin on Sat Dec 16 18:42:46 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_1-1_4507	4507 / 4507

Linkage	Site Range	Site Count
Phosphate	1_2-1_4507	4506 / 4506

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Human PPT1 (sense)	NUCLEIC ACID FEATURE

Kozak sequence (sense)	NUCLEIC ACID FEATURE

Human PPT1 (antisense)	NUCLEIC ACID FEATURE

wtITR (sense)	NUCLEIC ACID FEATURE

wtITR (antisense)	NUCLEIC ACID FEATURE

promoter region (sense)	NUCLEIC ACID FEATURE

promoter region (antisense)	NUCLEIC ACID FEATURE

bGH polyA (antisense)	NUCLEIC ACID FEATURE

mITR	NUCLEIC ACID FEATURE

Kozak sequence (antisense)	NUCLEIC ACID FEATURE

bGH polyA (sense)	NUCLEIC ACID FEATURE