U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 00:06:09 GMT 2023
Edited
by admin
on Sat Dec 16 00:06:09 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
U9JLP7V031
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEBRIKIZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
TNX-650
Code English
RO-5490255
Code English
RG-3637
Code English
lebrikizumab [INN]
Common Name English
Lebrikizumab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MOUSE MONOCLONAL MILR1444A .GAMMA.4-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL MILR1444A .KAPPA.-CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN INTERLEUKIN-13); HUMANIZED MOUSE MONOCLONAL MILR1444A (226-PROLINE(H(SUP 10)S>P)).GAMMA.4 HEAVY CHAIN (132-218')-DISULFIDE WITH HUMANIZED MOUSE MONOCLONAL MILR1444A .KAPPA. LIGHT CHAIN, DIMER (224-224'':227-227'')-BISDISULF
Common Name English
LEBRIKIZUMAB [JAN]
Common Name English
LEBRIKIZUMAB [USAN]
Common Name English
PRO-301444
Code English
MILR-1444A
Code English
PRO301444
Code English
MILR1444A
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
FDA ORPHAN DRUG 381112
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
Code System Code Type Description
USAN
UU-78
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
DRUG BANK
DB11914
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
INN
9165
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
CAS
953400-68-5
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
NCI_THESAURUS
C87767
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
FDA UNII
U9JLP7V031
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
WIKIPEDIA
LEBRIKIZUMAB
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
ChEMBL
CHEMBL1743035
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
ChEMBL
CHEMBL2109466
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
EVMPD
SUB177213
Created by admin on Sat Dec 16 00:06:09 GMT 2023 , Edited by admin on Sat Dec 16 00:06:09 GMT 2023
PRIMARY
From To
2_259 2_319
1_132 3_218
1_145 1_201
1_224 2_224
1_227 2_227
1_259 1_319
1_365 1_423
2_22 2_95
2_132 4_218
2_145 2_201
2_365 2_423
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL