LEBRIKIZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:31:11 GMT 2025` Edited by `admin` on `Mon Mar 31 20:31:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	U9JLP7V031
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

LEBRIKIZUMAB

Official Name

English

MILR-1444A

Preferred Name

English

TNX-650

Code

English

RO-5490255

Code

English

RG-3637

Code

English

lebrikizumab [INN]

Common Name

English

Lebrikizumab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MOUSE MONOCLONAL MILR1444A .GAMMA.4-CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL MILR1444A .KAPPA.-CHAIN, DIMER

Common Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN INTERLEUKIN-13); HUMANIZED MOUSE MONOCLONAL MILR1444A (226-PROLINE(H(SUP 10)S>P)).GAMMA.4 HEAVY CHAIN (132-218')-DISULFIDE WITH HUMANIZED MOUSE MONOCLONAL MILR1444A .KAPPA. LIGHT CHAIN, DIMER (224-224'':227-227'')-BISDISULF

Common Name

English

LEBRIKIZUMAB [JAN]

Common Name

English

LEBRIKIZUMAB [USAN]

Common Name

English

PRO-301444

Code

English

PRO301444

Code

English

MILR1444A

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

FDA ORPHAN DRUG

381112

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

Code System Code Type Description

USAN

UU-78

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

DRUG BANK

DB11914

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

INN

9165

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

SMS_ID

100000163087

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

CAS

953400-68-5

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

NCI_THESAURUS

C87767

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

FDA UNII

U9JLP7V031

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

WIKIPEDIA

LEBRIKIZUMAB

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

ChEMBL

CHEMBL1743035

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

ChEMBL

CHEMBL2109466

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

EVMPD

SUB177213

Created by admin on Mon Mar 31 20:31:11 GMT 2025 , Edited by admin on Mon Mar 31 20:31:11 GMT 2025

PRIMARY

From	To
2_259	2_319
1_132	3_218
1_145	1_201
1_224	2_224
1_227	2_227
1_259	1_319
1_365	1_423
2_22	2_95
2_132	4_218
2_145	2_201
2_365	2_423
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details

Lebrikizumab-LBKZ

SUB_CONCEPT->SUBSTANCE

Amount:


					JC88P1P6QM

HUMAN INTERLEUKIN 13

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					U9JLP7V031

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL