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Details

Stereochemistry ACHIRAL
Molecular Formula C12H20N2
Molecular Weight 192.3006
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TREMORINE

SMILES

C(C#CCN1CCCC1)N2CCCC2

InChI

InChIKey=JSUAJTLKVREZHV-UHFFFAOYSA-N
InChI=1S/C12H20N2/c1-2-8-13(7-1)11-5-6-12-14-9-3-4-10-14/h1-4,7-12H2

HIDE SMILES / InChI

Molecular Formula C12H20N2
Molecular Weight 192.3006
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Loss of thalamic serotonin transporters in early drug-naïve Parkinson's disease patients is associated with tremor: an [(123)I]beta-CIT SPECT study.
2008-05
Antiparkinsonian-like effects of Plumbago scandens on tremorine-induced tremors methodology.
2004-12
The spinal antinociceptive effects of cholinergic drugs in rats: receptor subtype specificity in different nociceptive tests.
2002-11-19
Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity.
2001-06-01
[Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor].
1976-04
Tremorine-oxotremorine-induced tremor, hypothermia and analgesia, and physostigmine toxicity, in mice after pretreatment with beta-adrenoceptor antagonists.
1976-04
1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases.
1971-11
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 21:21:01 GMT 2025
Edited
by admin
on Mon Mar 31 21:21:01 GMT 2025
Record UNII
U817VZ1URQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TREMORINE
MI  
Common Name English
NSC-407428
Preferred Name English
TREMORINE [MI]
Common Name English
1,1-(2-BUTYNE-1,4-DIYL)BISPYRROLIDINE
Common Name English
1,4-DIPYRROLIDINO-2-BUTYNE
Systematic Name English
1,4-DIPYRROLIDINYL-2-BUTYNE
Systematic Name English
TREMORIN
Common Name English
Code System Code Type Description
WIKIPEDIA
Tremorine
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
MERCK INDEX
m11014
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY Merck Index
FDA UNII
U817VZ1URQ
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
NSC
407428
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
PUBCHEM
5534
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
CAS
51-73-0
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
MESH
D014203
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY
EPA CompTox
DTXSID00199004
Created by admin on Mon Mar 31 21:21:01 GMT 2025 , Edited by admin on Mon Mar 31 21:21:01 GMT 2025
PRIMARY