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Details

Stereochemistry ACHIRAL
Molecular Formula C12H20N2
Molecular Weight 192.3006
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TREMORINE

SMILES

C(C#CCN1CCCC1)N2CCCC2

InChI

InChIKey=JSUAJTLKVREZHV-UHFFFAOYSA-N
InChI=1S/C12H20N2/c1-2-8-13(7-1)11-5-6-12-14-9-3-4-10-14/h1-4,7-12H2

HIDE SMILES / InChI

Molecular Formula C12H20N2
Molecular Weight 192.3006
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA-like compound, with potential use in extrapyramidal diseases.
1971 Nov
[Inhibition of harmaline induced tremor by L-threo-3, 4-dihydroxyphenylserine, an L-norepinephrine precursor].
1976 Apr
Tremorine-oxotremorine-induced tremor, hypothermia and analgesia, and physostigmine toxicity, in mice after pretreatment with beta-adrenoceptor antagonists.
1976 Apr
Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity.
2001 Jun 1
The spinal antinociceptive effects of cholinergic drugs in rats: receptor subtype specificity in different nociceptive tests.
2002 Nov 19
Antiparkinsonian-like effects of Plumbago scandens on tremorine-induced tremors methodology.
2004 Dec
Loss of thalamic serotonin transporters in early drug-naïve Parkinson's disease patients is associated with tremor: an [(123)I]beta-CIT SPECT study.
2008 May
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 04:14:28 GMT 2023
Edited
by admin
on Sat Dec 16 04:14:28 GMT 2023
Record UNII
U817VZ1URQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TREMORINE
MI  
Common Name English
TREMORINE [MI]
Common Name English
1,1-(2-BUTYNE-1,4-DIYL)BISPYRROLIDINE
Common Name English
NSC-407428
Code English
1,4-DIPYRROLIDINO-2-BUTYNE
Systematic Name English
1,4-DIPYRROLIDINYL-2-BUTYNE
Systematic Name English
TREMORIN
Common Name English
Code System Code Type Description
WIKIPEDIA
Tremorine
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
MERCK INDEX
m11014
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY Merck Index
FDA UNII
U817VZ1URQ
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
NSC
407428
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
PUBCHEM
5534
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
CAS
51-73-0
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
MESH
D014203
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID00199004
Created by admin on Sat Dec 16 04:14:28 GMT 2023 , Edited by admin on Sat Dec 16 04:14:28 GMT 2023
PRIMARY