Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H32O2.C4H11NO |
Molecular Weight | 345.5603 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(N)CO.CCCCCCCCCCCCCCCC(O)=O
InChI
InChIKey=JCAUMMFFSUIVSB-UHFFFAOYSA-N
InChI=1S/C16H32O2.C4H11NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18;1-4(2,5)3-6/h2-15H2,1H3,(H,17,18);6H,3,5H2,1-2H3
Molecular Formula | C16H32O2 |
Molecular Weight | 256.4241 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C4H11NO |
Molecular Weight | 89.1362 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Aminomethylpropanol is a synthetic ingredient that functions as a buffer to adjust the pH of cosmetics and personal care products. In cosmetics and personal care products, aminomethylpropanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products. The main function of aminomethylpropanol in these products is to establish and hold the pH. The Food and Drug Administration (FDA) includes aminomethylpropanol on its list of indirect food additives as a component of adhesives that are in contact with food. The European Chemicals Agency (ECHA) identifies that “substance causes serious eye irritation, is harmful to aquatic life with long lasting effects and causes skin irritation, causes serious eye damage.” Toxicologically significant concentrations of AMP are unlikely to be achieved in the systemic circulation and/or target tissues in humans as a result of dermal application of products containing aminomethylpropanol. Systemically absorbed dose will be rapidly eliminated from the body with little remaining at the application site.
Approval Year
PubMed
Title | Date | PubMed |
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[Influences of uncommon isoenzymes on determination of alkaline phosphatase activity by dry-chemistry analyzers]. | 2001 Apr |
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Alkaline phosphatase activity: new assay for the Reflotron system. Results of the evaluation in eight clinical laboratories. | 2001 Jan |
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Preparation and characterisation of a range of diclofenac salts. | 2001 Sep 11 |
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Poly(amide ester)s from 2,6-pyridinedicarboxylic acid and ethanolamine derivatives: identification of macrocycles by matrix-assisted laser desorption/ionization mass spectrometry. | 2002 |
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Vascular responsiveness to dimethylaminoethyl methacrylate and its degradation products. | 2003 Jul 1 |
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Facile syntheses of oxazolines and thiazolines with N-acylbenzotriazoles under microwave irradiation. | 2004 Feb 6 |
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Determination of carbon dioxide and acid components in exhaust gas by suppressed ion chromatography. | 2004 Jan |
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Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet. | 2004 Mar 22 |
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Synthesis of levan in water-miscible organic solvents. | 2004 Oct 19 |
|
Rhodovarius lipocyclicus gen. nov. sp. nov., a new genus of the alpha-1 subclass of the Proteobacteria. | 2004 Sep |
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ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes. | 2004 Sep 28 |
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Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growth. | 2005 Apr 22 |
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Comparative analysis of mouse skeletal muscle fibre type composition and contractile responses to calcium channel blocker. | 2005 Feb 14 |
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Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. | 2005 Mar |
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Proteomic analysis of plasma membrane and secretory vesicles from human neutrophils. | 2007 Aug 10 |
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2-(2-Methoxy-phen-yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole. | 2007 Dec 6 |
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Synthesis and characterization of a new layered fluoroaluminophosphate (C4H11NOH)3.5[Al4(PO4)5F] x 0.5H3O with extra-large 16-rings. | 2007 Jan 8 |
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Micro-morphologic changes around biophysically-stimulated titanium implants in ovariectomized rats. | 2007 Jul 16 |
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Oxidation of N-nitrosodimethylamine (NDMA) precursors with ozone and chlorine dioxide: kinetics and effect on NDMA formation potential. | 2007 Mar 15 |
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[Study of new blended chemical absorbents to absorb CO2]. | 2007 Nov |
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Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors. | 2007 Oct 9 |
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Pharmacokinetics of aminomethylpropanol in rats following oral and a novel dermal study design. | 2008 Feb |
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Does Litomosoides sigmodontis synthesize dimethylethanolamine from choline? | 2008 Jan |
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1-Hydroxymethyl-1-methylethan-aminium chloride. | 2008 May 24 |
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Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008 Nov 22 |
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Removal characteristics of CO2 using aqueous MEA/AMP solutions in the absorption and regeneration process. | 2009 |
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Serotonin increases cilia-driven particle transport via an acetylcholine-independent pathway in the mouse trachea. | 2009 |
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Optimization of automated large-scale production of [(18)F]fluoroethylcholine for PET prostate cancer imaging. | 2009 Jul |
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Influence of fluorocarbon flat-membrane hydrophobicity on carbon dioxide recovery. | 2009 Jun |
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Isolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization. | 2009 Jun 5 |
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1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodeca-hydro-phenanthrene-1-carboxylic acid. | 2009 May 29 |
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Capture of carbon dioxide by amine-impregnated as-synthesized MCM-41. | 2010 |
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Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha. | 2010 Apr |
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Harmonization of values for serum alkaline phosphatase catalytic activity concentration employing commutable calibration materials. | 2010 Jun 3 |
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Evaluation of alkanolamine solutions for carbon dioxide removal in cross-flow rotating packed beds. | 2010 Mar 15 |
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N-(2-Hy-droxy-1,1-dimethyl-eth-yl)-benzene-sulfonamide. | 2010 Oct 31 |
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Distinguishing between maternally-mediated and directly embryotoxic modes-of-action for postimplantation loss induced in rats by 2-amino-2-methylpropanol. | 2014 Nov |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17961896
Curator's Comment: rat data
18 mg/kg in water
Route of Administration:
Other
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 19:06:05 GMT 2023
by
admin
on
Sat Dec 16 19:06:05 GMT 2023
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Record UNII |
U7RH9E458D
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Record Status |
Validated (UNII)
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Record Version |
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