PEGLOPRASTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:23:02 GMT 2025` Edited by `admin` on `Wed Apr 02 02:23:02 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	U6M486P0QJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PEGLOPRASTIDE

Official Name

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-METHYL-.OMEGA.-HYDROXY-, 6-ESTER WITH N-(6-(2-(7-(1-ETHYL-1,3-DIHYDRO-3,3-DIMETHYL-5-SULFO-2H-INDOL-2-YLIDENE)-1,3,5-HEPTATRIEN-1-YL)-3,3-DIMETHYL-5-SULFOINDOLIO)-1-OXOHEXYL)-D-.ALPHA.-GLUTAMYL-D-.ALPHA.-GLUTAMYL-D-.ALPH

Preferred Name

English

pegloprastide [INN]

Common Name

English

AVB-620

Code

English

PEGLOPRASTIDE [USAN]

Common Name

English

AVB620

Code

English

Code System Code Type Description

USAN

JK-243

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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CAS

2138471-65-3

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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FDA UNII

U6M486P0QJ

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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SMS_ID

300000005880

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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NCI_THESAURUS

C170299

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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INN

10946

Created by admin on Wed Apr 02 02:23:02 GMT 2025 , Edited by admin on Wed Apr 02 02:23:02 GMT 2025

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Related Record Type Details


					U6M486P0QJ

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_22]	C-TERMINUS			D-CYSTEINAMIDE, PEGLOPRASTIDE-	Y6M0UK0DK1
AMINO_ACID_SUBSTITUTION	[1_11]	SITE_SPECIFIC			S-METHYLCYSTEINE	A34I1H07YM
AMINO_ACID_SUBSTITUTION	[1_7]	SITE_SPECIFIC			2-AMINOETHOXYACETIC ACID	0VKE1SR1DR
PEGYLATION	[1_6]	SITE_SPECIFIC			M-PEG-2000-CARBAMOYL-ETHYL-PARA-ACETOXIME-PHENYLALANINE	J4VL0X8CZJ
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			D-GLUTAMIC ACID, PEGLOPRASTIDE-	JXT77QU2W5

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL