U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H24N2O2.ClH
Molecular Weight 360.878
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VIQUIDIL HYDROCHLORIDE

SMILES

Cl.COC1=CC=C2N=CC=C(C(=O)CC[C@@H]3CCNC[C@@H]3C=C)C2=C1

InChI

InChIKey=YUBRJAHSRSIPKX-LDXVYITESA-N
InChI=1S/C20H24N2O2.ClH/c1-3-14-13-21-10-8-15(14)4-7-20(23)17-9-11-22-19-6-5-16(24-2)12-18(17)19;/h3,5-6,9,11-12,14-15,21H,1,4,7-8,10,13H2,2H3;1H/t14-,15+;/m0./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C20H24N2O2
Molecular Weight 324.4168
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Viquidil is an isomer of quinidine and papaverine derivative. Viquidil is used for treatment of disturbances of cerebral blood flow and metabolism. Viquidil, however, appeared to be approximately twice as potent as papaverine in inhibition of thrombus formation in the microvasculature and was apparently without toxic side-effects.

Approval Year

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Hamster data
Minimum dose level - 2.5 X 10(-4) mg/kg
Route of Administration: Parenteral
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:26:20 GMT 2023
Edited
by admin
on Sat Dec 16 01:26:20 GMT 2023
Record UNII
U6FXT2V136
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VIQUIDIL HYDROCHLORIDE
MI   WHO-DD  
Common Name English
1-PROPANONE, 3-((3R,4R)-3-ETHENYL-4-PIPERIDINYL)-1-(6-METHOXY-4-QUINOLINYL)-, MONOHYDROCHLORIDE
Common Name English
1-PROPANONE, 3-(3-ETHENYL-4-PIPERIDINYL)-1-(6-METHOXY-4-QUINOLINYL)-, MONOHYDROCHLORIDE, (3R-CIS)-
Common Name English
VIQUIDIL HCL
Common Name English
QUINICINE HYDROCHLORIDE
Common Name English
PERMIRAN
Common Name English
Viquidil hydrochloride [WHO-DD]
Common Name English
CHINOTOXIN
Common Name English
QUINOTOXINE HYDROCHLORIDE
Common Name English
VIQUIDIL HYDROCHLORIDE [MI]
Common Name English
Code System Code Type Description
RXCUI
236343
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY RxNorm
EPA CompTox
DTXSID30966589
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
PUBCHEM
198279
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
CAS
52211-63-9
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
SMS_ID
100000087884
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
EVMPD
SUB05109MIG
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
FDA UNII
U6FXT2V136
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
MERCK INDEX
m11469
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
257-739-9
Created by admin on Sat Dec 16 01:26:20 GMT 2023 , Edited by admin on Sat Dec 16 01:26:20 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY