Gocatamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 08:29:29 GMT 2025` Edited by `admin` on `Wed Apr 02 08:29:29 GMT 2025`
Protein Type	TRISPECIFIC ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	U6CKL88C8H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IG single chain scFvhl-VH-VH' (1-505) [scFvhl anti-CD3E (1-149) [VH Musmus/Homsap (Mus musculus IGHV10-1*02 (89.9%) -(IGHD) -IGHJ3*01 (100%)/Homo sapiens IGHV3-73*01 (85.0%) -(IGHD) -IGHJ5*01 (100%), CDR-IMGT [8.10.16] (26-33.51-60.99-114)) (1-125) -15-m

Preferred Name

English

Gocatamig

Official Name

English

Immunoglobulin, trispecific, anti-(human CD3 antigen-chain) (human-Mus musculus monoclonal HPN328 single-chain variable fragment VH-(GGGGS)-VL) fusion protein with peptide linker (GGGGSGGGS) fusion protein with immunoglobulin anti-(human albumin) (human-

Common Name

English

immunoglobulin single chain scFvhl-VH-VH', anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)], anti-[Homo sapiens ALB (albumin, human serum albumin, HSA)] and anti-[Homo sapiens DLL3 (delta-like ligand 3, delta like canonical Notch ligand 3)], trispecific

Common Name

English

Tri-specific T cell activating construct targeting DLL3, HSA, and CD3e

Common Name

English

gocatamig [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

864721