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SARUPLASE
U5NH2JV64T
Possibly Marketed Outside US
General
Record Details
Names
10
Classification
3
Identifiers
9
Subunits
1
Disulfide Links
12
Active Moiety
1
Characteristic Attributes
2
SARUPLASE
U5NH2JV64T
Possibly Marketed Outside US
General
Approval Year
Unknown
139,594
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
U5NH2JV64T
Record Status
Validated (UNII)
Record Version
11
10
9
8
7
6
5
4
3
2
1
Names
10
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entries
Name
Type
Language
Name
Type
Language
SARUPLASE
Official Name
English
SINGLE CHAIN UROKINASE PLASMINOGEN ACTIVATOR
Common Name
English
saruplase [INN]
Common Name
English
PROUROKINASE (ENZYME ACTIVATING) (HUMAN CLONE PUK4/PUK18), NONGLYCOSYLATED
Common Name
English
KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK33 REDUCED)
Common Name
English
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Classification
3
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Designated
ORPHAN DRUG
Designated
Treatment of empyema (pleural)
FDA ORPHAN DRUG
442514
Enzymes
ATC
BLOOD AND BLOOD FORMING ORGANS
ANTITHROMBOTIC AGENTS
ANTITHROMBOTIC AGENTS
Enzymes
saruplase
WHO-ATC
B01AD08
Agent Affecting Blood or Body Fluid
Pharmacologic Substance
[C1909]
Agent Affecting Blood or Body Fluid
[C78275]
Thrombolytic Agent
NCI_THESAURUS
C29750
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Identifiers
9
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Code System
Code
Type
Description
Code System
Code
Type
Description
INN
6192
PRIMARY
CAS
99149-95-8
PRIMARY
WIKIPEDIA
SARUPLASE
PRIMARY
ChEMBL
CHEMBL2108129
PRIMARY
EVMPD
SUB10456MIG
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Disulfide Links
12
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entries
From
To
From
To
1_11
1_19
1_13
1_31
1_33
1_42
1_50
1_131
1_71
1_113
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3
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
U5NH2JV64T
SARUPLASE
ACTIVE MOIETY
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C2031H3126N585O601S31
MOL_WEIGHT:SEQUENCE(CALCULATED)
CHEMICAL
SEQUENCE 46368 DA (average)
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