GET-73 (N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide) is a compound with a structure related to that of gamma-hydroxybutyric acid (GHB), which is used in the treatment of alcohol withdrawal. Like GHB, GET-73 has the capacity to reduce alcohol intake in rats. GET-73 also exerts anxiolytic effects in rats and seemed to improve memory in a water maze test. Although the exact mechanism of GET-73 action is still unknown, it was suggested that an allosteric modulation of metabotropic glutamate receptor 5 (mGlu5 receptor) by GET-73 may represent the mechanism underlying the effects of the compound. GET73 was suggested to have a multifaceted pharmacological profile, importantly including the capacity to reduce alcohol drinking and anxiety-related behaviors. A phase II study was completed in November 2018, in which physical effects and changes in cognitive performance as a result of GET-73 administration were studied in alcohol-dependent individuals.