U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:16:17 GMT 2023
Edited
by admin
on Sat Dec 16 14:16:17 GMT 2023
Protein Type RECEPTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
U590IVB1UR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
S-ARRESTIN
Common Name English
RETINAL S-ANTIGEN
Common Name English
ROD PHOTORECEPTOR ARRESTIN
Common Name English
Code System Code Type Description
FDA UNII
U590IVB1UR
Created by admin on Sat Dec 16 14:16:17 GMT 2023 , Edited by admin on Sat Dec 16 14:16:17 GMT 2023
PRIMARY
UNIPROT
P10523
Created by admin on Sat Dec 16 14:16:17 GMT 2023 , Edited by admin on Sat Dec 16 14:16:17 GMT 2023
PRIMARY
Related Record Type Details
MIMETIC->TARGET
A small peptide that has been shown to mimic the retinal S-antigen, the offending protein antigen responsible for the ocular inflammation. Intraocular uveitis appears to result from an autoimmune reaction to antigens in the eye, specifically the S-antigen and the interphotoreceptor-retinoid-binding-protein (IRBP). OptiquelT has been designed to down regulate this undesired autoimmune response by inducing a specific immune tolerance to the retinal S-antigen.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL