Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H8N2 |
| Molecular Weight | 144.1732 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=C2N=CC=CC2=CC=C1
InChI
InChIKey=WREVVZMUNPAPOV-UHFFFAOYSA-N
InChI=1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
| Molecular Formula | C9H8N2 |
| Molecular Weight | 144.1732 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The reality of using primaquine. | 2010-12-27 |
|
| Mechanism of interaction of sitamaquine with Leishmania donovani. | 2010-12 |
|
| Operational strategies to achieve and maintain malaria elimination. | 2010-11-06 |
|
| Cascading transformations within a dynamic self-assembled system. | 2010-08 |
|
| From sensors to silencers: quinoline- and benzimidazole-sulfonamides as inhibitors for zinc proteases. | 2010-06-23 |
|
| The impact of phenotypic and genotypic G6PD deficiency on risk of plasmodium vivax infection: a case-control study amongst Afghan refugees in Pakistan. | 2010-05-25 |
|
| Both visual and fluorescent sensor for Zn2+ based on quinoline platform. | 2010-05-03 |
|
| Drug resistance in leishmaniasis. | 2010-05 |
|
| Treatment of visceral leishmaniasis. | 2010-05 |
|
| Chloroquine and its derivatives exacerbate B19V-associated anemia by promoting viral replication. | 2010-04-27 |
|
| A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. | 2010-04-06 |
|
| Direct analysis of dried blood spots utilizing desorption electrospray ionization (DESI) mass spectrometry. | 2010-04 |
|
| Auxiliary-assisted palladium-catalyzed arylation and alkylation of sp2 and sp3 carbon-hydrogen bonds. | 2010-03-24 |
|
| Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination. | 2010-03 |
|
| Bis[2-(8-quinolylimino-meth-yl)phenolato-κN,N',O]iron(III) azide. | 2010-01-27 |
|
| 2,4-Dichloro-6-(8-quinolylamino-methyl-ene)cyclo-hexa-2,4-dien-1-one methanol solvate. | 2010-01-23 |
|
| Control of visceral leishmaniasis in latin america-a systematic review. | 2010-01-19 |
|
| Solid-phase extractors based on 8-aminoquinoline and 2-aminopyridine covalently bonded to silica gel for the selective separation and determination of calcium in natural water and pharmaceutical samples. | 2010 |
|
| Palladium-catalyzed aryl C-H bonds activation/acetoxylation utilizing a bidentate system. | 2009-12-17 |
|
| Direct quantitative bioanalysis of drugs in dried blood spot samples using a thin-layer chromatography mass spectrometer interface. | 2009-12-15 |
|
| Bis(N-triisopropyl-silyl-quinolin-8-aminato)nickel(II). | 2009-12-04 |
|
| Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. | 2009-11-18 |
|
| Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes. | 2009-11-15 |
|
| Synthesis and characterization of organoaluminum compounds containing quinolin-8-amine derivatives and their catalytic behaviour for ring-opening polymerization of epsilon-caprolactone. | 2009-11-07 |
|
| Application of a liquid extraction based sealing surface sampling probe for mass spectrometric analysis of dried blood spots and mouse whole-body thin tissue sections. | 2009-11-01 |
|
| The synthesis and coordination chemistry of a tris-8-aminoquinoline tripodal ligand. | 2009-10-21 |
|
| Antimalarials and the fight against malaria in Brazil. | 2009-08 |
|
| Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations. | 2009-07-15 |
|
| Electrochemistry of ruthenium(II) complexes of 8-aminoquinoline. | 2009-05-14 |
|
| N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents. | 2009-05 |
|
| Pharmacotherapeutic options for visceral leishmaniasis-current scenario. | 2009-01-23 |
|
| Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin. | 2009 |
|
| Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives. | 2009 |
|
| The role of anti-malarial drugs in eliminating malaria. | 2008-12-11 |
|
| Selection of the most promising 2-substituted quinoline as antileishmanial candidate for clinical trials. | 2008-12 |
|
| Identification of differentially expressed genes after acute exposure to bulaquine (CDRI 80/53) in mice liver. | 2008-12 |
|
| Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine. | 2008-10 |
|
| Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511). | 2008-09 |
|
| In vitro antileishmanial activity of fluoro-artemisinin derivatives against Leishmania donovani. | 2008-09 |
|
| Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines. | 2008-09 |
|
| Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki. | 2008-08 |
|
| Effects of amino acids on malarial heme crystallization. | 2008-08 |
|
| 8-Quinolylguanidinium chloride. | 2008-06-07 |
|
| One-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with 8-hydroxyquinoline, 8-aminoquinoline and quinoline-2-carboxylic acid (quinaldic acid). | 2008-03 |
|
| Selection and phenotype characterisation of sitamaquine-resistant promastigotes of Leishmania donovani. | 2008-03 |
|
| N,N'-Bis(8-quinol-yl)pyridine-2,6-dicarboxamide. | 2008-01-11 |
|
| Primaquine-induced differential gene expression analysis in mice liver using DNA microarrays. | 2007-09-24 |
|
| Response to malaria epidemics in Africa. | 2007-05 |
|
| Tafenoquine: a promising new antimalarial agent. | 2007-05 |
|
| Drug development papers in PLoS Medicine: how we try to spot a winner. | 2006-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:41:28 GMT 2025
by
admin
on
Mon Mar 31 18:41:28 GMT 2025
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| Record UNII |
U34EAV21TG
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| Record Status |
Validated (UNII)
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11359
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36709
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8-AMINOQUINOLINE
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209-427-9
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