DISODIUM OCTABORATE TETRAHYDRATE

US Previously Marketed

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	B8O13.2Na.4H2O
Molecular Weight	412.521
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DISODIUM OCTABORATE TETRAHYDRATE

Structure Search

SMILES

O.O.O.O.[Na+].[Na+].[O-]B1OB(OB=O)OB2OB([O-])OB(OB=O)OB(O1)O2

InChI

InChIKey=QZPOVOYJRLCVLA-UHFFFAOYSA-N

InChI=1S/B8O13.2Na.4H2O/c9-1-13-5-15-3(11)17-8-20-6(14-2-10)16-4(12)18-7(19-5)21-8;;;;;;/h;;;4*1H2/q-2;2*+1;;;;

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	B8H2O13
Molecular Weight	296.496
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=IndirectAdditives&id=AMMONIUMBORATE | https://www.drugfuture.com/chemdata/ammonium-borate.html

AMMONIUM BORATE is used in fireproofing wood and textiles, and also in electrolytic condensers. It can be indirect additive used in food contact substances.

Approval Year

PubMed

Title	Date	PubMed
The Effects of Boron on Arsenic-Induced Lipid Peroxidation and Antioxidant Status in Male and Female Rats.	2015-12	26184899
Comparison of osteoblast and cardiomyocyte differentiation in the embryonic stem cell test for predicting embryotoxicity in vivo.	2014-09	24704097
Assessment of developmental delay in the zebrafish embryo teratogenicity assay.	2013-02	22898132
Protective effect of boric acid against carbon tetrachloride-induced hepatotoxicity in mice.	2012-07	21999471
Boric acid increases the expression levels of human anion exchanger genes SLC4A2 and SLC4A3.	2012-04-03	22576912
Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.	2011-04	21232540
Experimental study on the estrogen-like effect of boric Acid.	2008-02	17943231
Boric acid inhibits LPS-induced TNF-alpha formation through a thiol-dependent mechanism in THP-1 cells.	2008	18755394
Boric acid inhibits embryonic histone deacetylases: a suggested mechanism to explain boric acid-related teratogenicity.	2007-04-15	17320131
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Defects in cervical vertebrae in boric acid-exposed rat embryos are associated with anterior shifts of hox gene expression domains.	2003-01	12749385
Boron modulates extracellular matrix and TNF alpha synthesis in human fibroblasts.	1998-05-29	9618283
Advances in understanding mechanisms of toxicity and implications for risk assessment.	1997-03-01	9100314
Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants.	1992	1288759

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:46:04 GMT 2025` Edited by `admin` on `Mon Mar 31 21:46:04 GMT 2025`
Record UNII	U2EEC8170G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DISODIUM OCTABORATE TETRAHYDRATE

Systematic Name

English

BORACOL

Preferred Name

English

TIM-BOR

Brand Name

English

EPA PESTICIDE CHEMICAL CODE 011103

Code

English

BORON SODIUM OXIDE, TETRAHYDRATE

Common Name

English

FLEABOR

Brand Name

English

BORON SODIUM OXIDE TETRAHYDRATE

Common Name

English

POLYBOR 3

Brand Name

English

CELLU-TREAT

Brand Name

English

BORIC ACID (H2B8O13), DISODIUM SALT, TETRAHYDRATE

Systematic Name

English

NIBOR-D

Brand Name

English

MOP UP

Brand Name

English

BORON SODIUM OXIDE (B8NA2O13), TETRAHYDRATE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

11103