IODOMETOMIDATE I-123, R-

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H13IN2O2
Molecular Weight	356.159
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC(=O)C1=CN=CN1[C@H](C)C2=CC=C(I)C=C2

InChI

InChIKey=KECBLXVYTIVCTG-SECBINFHSA-N

InChI=1S/C13H13IN2O2/c1-9(10-3-5-11(14)6-4-10)16-8-15-7-12(16)13(17)18-2/h3-9H,1-2H3/t9-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C13H13IN2O2
Molecular Weight	356.159
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23609836 | https://www.ncbi.nlm.nih.gov/pubmed/23426614 | https://www.ncbi.nlm.nih.gov/pubmed/23343186 | https://clinicaltrials.gov/ct2/show/NCT02010957

Iodometomidate I-123, R- (also known as ) is phenylethylimidazole derivative studied as a diagnostic agent for adrenal imaging. Iodometomidate is a highly suitable tracer combining specific uptake in adrenocortical tissue with far lower radiation exposure compared to norcholesterol scintigraphy. Phase III clinical trial for Adrenal Gland Neoplasms imaging is currently ongoing.

Originator

Approval Year

PubMed

Title	Date	PubMed
[¹²³I]Iodometomidate imaging in adrenocortical carcinoma.	2013 Jul	23609836

Patents

Sample Use Guides

In Vivo Use Guide

185 MBq

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:18:41 GMT 2023` Edited by `admin` on `Fri Dec 15 15:18:41 GMT 2023`
Record UNII	U21CVV13SV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IODOMETOMIDATE I-123, R-

Common Name

English

123I-IODOMETOMIDATE

Common Name

English

1H-IMIDAZOLE-5-CARBOXYLIC ACID, 1-((1R)-1-(4-IODOPHENYL)ETHYL)-, METHYL ESTER

Common Name

English

(R)-4-(123I)IODOMETOMIDATE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID50231064