U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Na.HO3S
Molecular Weight 104.061
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Sodium bisulfite

SMILES

[Na+].OS([O-])=O

InChI

InChIKey=DWAQJAXMDSEUJJ-UHFFFAOYSA-M
InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula HO3S
Molecular Weight 81.071
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Diammonium sulfite monohydrate (Ammonium sulfite monohydrate) has a wide use of applications, such as hair straightening or waving agents, as an ingredient in carmel food coloring, as well as an reducing agent in photography. Other applications include lubricants for cold metal working and blast furnace linings. It is considered safe as used in cosmetic formulations.

Approval Year

1939
36
PubMed

PubMed

TitleDatePubMed
Effects of pH on the formation of 4(5)-Methylimidazole in glucose/ammonium sulfate and glucose/ammonium sulfite caramel model reactions.
2015-10
Novel homogeneous catalyst system for the oxidation of concentrated ammonium sulfite.
2006-02-28
Final report on the safety assessment of sodium sulfite, potassium sulfite, ammonium sulfite, sodium bisulfite, ammonium bisulfite, sodium metabisulfite and potassium metabisulfite.
2003
Patents

Patents

06867320
10
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:32:59 GMT 2025
Edited
by admin
on Mon Mar 31 18:32:59 GMT 2025
Record UNII
TZX5469Z6I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Sodium bisulfite
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
E-222
Preferred Name English
MONOSODIC SULPHITE
Common Name English
INS-222
Code English
SULFUROUS ACID, MONOSODIUM SALT
Common Name English
SODIUM HYDROGEN SULFITE
Systematic Name English
INS NO.222
Code English
SULFUROUS ACID, SODIUM SALT (1:1)
Common Name English
SODIUM BISULFITE [VANDF]
Common Name English
SODIUM BISULFITE [JAN]
Common Name English
SODIUM HYDROGEN SULPHITE
Systematic Name English
NSC-60680
Code English
SODIUM BISULFITE [II]
Common Name English
SODIUM BISULFITE [FCC]
Common Name English
SODIUM BISULFITE [MART.]
Common Name English
SODIUM BISULFITE [MI]
Common Name English
SODIUM BISULFITE [HSDB]
Common Name English
SODIUM BISULPHITE
Systematic Name English
Monosodium sulfite
Systematic Name English
Sodium bisulfite [WHO-DD]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 78201
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-222
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
JECFA EVALUATION INS-222
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
Code System Code Type Description
ECHA (EC/EINECS)
231-548-0
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
RXCUI
1366858
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
EVMPD
SUB63257
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
EPA CompTox
DTXSID8034902
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
NCI_THESAURUS
C73837
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
DRUG BANK
DB14015
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
FDA UNII
TZX5469Z6I
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
WIKIPEDIA
SODIUM BISULFITE
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
MERCK INDEX
m9994
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY Merck Index
HSDB
724
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
SMS_ID
100000078082
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
CAS
7631-90-5
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
PUBCHEM
18000336
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
CONCEPT Industrial Aid
DAILYMED
TZX5469Z6I
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
ChEMBL
CHEMBL1689285
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
RXCUI
36679
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
ALTERNATIVE
MESH
C009279
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
NSC
60680
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
CHEBI
26709
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
EVMPD
SUB15272MIG
Created by admin on Mon Mar 31 18:32:59 GMT 2025 , Edited by admin on Mon Mar 31 18:32:59 GMT 2025
PRIMARY
Related Record Type Details
Structure of BISULFITE ION
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of BISULFITE ION
ACTIVE MOIETY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966