TECHNETIUM TC-99M 5-OXA-PNAO

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H27N7O5.OTc
Molecular Weight	512.3351
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	2
Charge	1

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M 5-OXA-PNAO

Structure Search

SMILES

O=[99Tc+3].C\C(=N/[O-])C(C)(C)NCC(CN1C=CN=C1[N+]([O-])=O)ONC(C)(C)C(\C)=N\[O-]

InChI

InChIKey=YCWYKEIFNMLCQH-KQKUEPDFSA-L

InChI=1S/C16H29N7O5.O.Tc/c1-11(19-24)15(3,4)18-9-13(28-21-16(5,6)12(2)20-25)10-22-8-7-17-14(22)23(26)27;;/h7-8,13,18,21,24-25H,9-10H2,1-6H3;;/q;;+3/p-2/b19-11+,20-12+;;/i;;1+1

HIDE SMILES / InChI

Molecular Formula	C16H27N7O5
Molecular Weight	397.4295
Charge	-2
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	2
Optical Activity	( + / - )

Molecular Formula	OTc
Molecular Weight	114.9057
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
bone problems 40 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8583	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 40 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8583	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012-10	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:31:29 GMT 2025` Edited by `admin` on `Mon Mar 31 18:31:29 GMT 2025`
Record UNII	TZI66E7CFY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECHNETIUM TC-99M 5-OXA-PNAO

Common Name

English

BMS-194796

Preferred Name

English

99MTC-5-OXA-PNAO

Common Name

English

BRU-59-21

Code

English

TECHNETIUM-99MTC, (3-((1-(((2-(HYDROXYIMINO-.KAPPA.N)-1,1-DIMETHYLPROPYL)AMINO-.KAPPA.N)METHYL)-2-(2-NITRO-1H-IMIDAZOL-1-YL)ETHOXY)AMINO-.KAPPA.N)-3-METHYL-2-BUTANONE OXIMATO(3-)-.KAPPA.N)OXO-, (SP-5-14)-

Systematic Name

English

Code System Code Type Description

CAS

161537-77-5

Created by admin on Mon Mar 31 18:31:29 GMT 2025 , Edited by admin on Mon Mar 31 18:31:29 GMT 2025

PRIMARY

PUBCHEM

138756755

Created by admin on Mon Mar 31 18:31:29 GMT 2025 , Edited by admin on Mon Mar 31 18:31:29 GMT 2025

PRIMARY

FDA UNII

TZI66E7CFY

Created by admin on Mon Mar 31 18:31:29 GMT 2025 , Edited by admin on Mon Mar 31 18:31:29 GMT 2025

PRIMARY

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					6EW75241VU

TECHNETIUM TC-99M

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Conditions

Approved Use

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Approved Use

Launch Date

PubMed

Patents

Sample Use Guides