U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H19NO2.ClH
Molecular Weight 269.767
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORMEPERIDINE HYDROCHLORIDE

SMILES

Cl.CCOC(=O)C1(CCNCC1)C2=CC=CC=C2

InChI

InChIKey=BBWMASBANDIFMV-UHFFFAOYSA-N
InChI=1S/C14H19NO2.ClH/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12;/h3-7,15H,2,8-11H2,1H3;1H

HIDE SMILES / InChI

Molecular Formula C14H19NO2
Molecular Weight 233.3062
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer.
1977 Jun
Normeperidine toxicity.
1986 May
Possible roles of normeperidine and hyponatremia in a postoperative death.
1987 Nov 15
Norpethidine induced myoclonus in a patient with renal failure.
1989 Dec
Normorphine, a neurotoxic metabolite?
1990 Mar 24
Toxicity of norpethidine in sickle cell crisis.
1992 Jun 6
Norpethidine accumulation and generalized seizure during pethidine patient-controlled analgesia.
1999 Jun
Seizures due to norpethidine toxicity.
2000 Aug
Successful treatment of normeperidine neurotoxicity by hemodialysis.
2000 Jan
Cerebellar and oculomotor dysfunction induced by rapid infusion of pethidine.
2014 Mar 11
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 11:28:11 GMT 2023
Edited
by admin
on Sat Dec 16 11:28:11 GMT 2023
Record UNII
TZ9K6J4X8J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORMEPERIDINE HYDROCHLORIDE
Common Name English
PETHIDINE INTERMEDIATE B HYDROCHLORIDE
Common Name English
ISONIPECOTIC ACID, 4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 4-PHENYL-, ETHYL ESTER, HYDROCHLORIDE (1:1)
Systematic Name English
NORPETHIDINE HYDROCHLORIDE
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
246-276-8
Created by admin on Sat Dec 16 11:28:11 GMT 2023 , Edited by admin on Sat Dec 16 11:28:11 GMT 2023
PRIMARY
CAS
24465-45-0
Created by admin on Sat Dec 16 11:28:11 GMT 2023 , Edited by admin on Sat Dec 16 11:28:11 GMT 2023
PRIMARY
FDA UNII
TZ9K6J4X8J
Created by admin on Sat Dec 16 11:28:11 GMT 2023 , Edited by admin on Sat Dec 16 11:28:11 GMT 2023
PRIMARY
PUBCHEM
32413
Created by admin on Sat Dec 16 11:28:11 GMT 2023 , Edited by admin on Sat Dec 16 11:28:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID60947361
Created by admin on Sat Dec 16 11:28:11 GMT 2023 , Edited by admin on Sat Dec 16 11:28:11 GMT 2023
PRIMARY
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