FURTERENE

Possibly Marketed Outside US

First approved in 2023

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H9N7O
Molecular Weight	243.2248
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(N=C(C3=CC=CO3)C(N)=N2)C(N)=N1

InChI

InChIKey=HCNBCFYKPSFHLH-UHFFFAOYSA-N

InChI=1S/C10H9N7O/c11-7-5(4-2-1-3-18-4)14-6-8(12)16-10(13)17-9(6)15-7/h1-3H,(H6,11,12,13,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C10H9N7O
Molecular Weight	243.2248
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5981331 | https://www.ncbi.nlm.nih.gov/pubmed/5976776 | https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C65791 | https://pubchem.ncbi.nlm.nih.gov/compound/Furterene

Furterene is a diuretic of the aminopteridine series, with aldosterone antagonist activity. Furterene is able to antagonize aldosterone at the mineralocorticoid receptor in the kidneys. It thereby increases sodium excretion while inhibiting potassium excretion.

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:29:14 UTC 2023` Edited by `admin` on `Fri Dec 15 15:29:14 UTC 2023`
Record UNII	TY1X1WG26A
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FURTERENE

Official Name

English

2,4,7-TRIAMINO-6-(2-FURYL)PTERIDINE

Systematic Name

English

furterene [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C448