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Details

Stereochemistry ACHIRAL
Molecular Formula C18H24NO.Cl
Molecular Weight 305.842
Optical Activity NONE
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEFENIDRAMIUM CHLORIDE

SMILES

[Cl-].C[N+](C)(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=ALVBFMLSZYRVDP-UHFFFAOYSA-M
InChI=1S/C18H24NO.ClH/c1-19(2,3)14-15-20-18(16-10-6-4-7-11-16)17-12-8-5-9-13-17;/h4-13,18H,14-15H2,1-3H3;1H/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula Cl
Molecular Weight 35.453
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H24NO
Molecular Weight 270.3893
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity NONE

Description

Mefenidramium is an active ingredient of the Danish drug Paradryl that was used to treat pruritus with varicella and as a palliative treatment of estival rhinitis in children.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Behavioral thermoregulation in the study of drugs affecting body temperature.
1975-11-01
[Paradryl salve and ido tar, two new preparations for Besnier's prurigo and eczema].
1951-11-29
Paradryl ointment and Ido tar; two new remedies for the treatment of Besnier's prurigo and eczema.
1951
Substance Class Chemical
Created
by admin
on Wed Apr 02 18:47:27 GMT 2025
Edited
by admin
on Wed Apr 02 18:47:27 GMT 2025
Record UNII
TXS7AH2C5Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEFENIDRAMIUM CHLORIDE
Common Name English
Ammonium, [2-(diphenylmethoxy)ethyl]trimethyl-, chloride
Preferred Name English
Ethanaminium, 2-(diphenylmethoxy)-N,N,N-trimethyl-, chloride (1:1)
Systematic Name English
Code System Code Type Description
CAS
23362-78-9
Created by admin on Wed Apr 02 18:47:27 GMT 2025 , Edited by admin on Wed Apr 02 18:47:27 GMT 2025
PRIMARY
FDA UNII
TXS7AH2C5Z
Created by admin on Wed Apr 02 18:47:27 GMT 2025 , Edited by admin on Wed Apr 02 18:47:27 GMT 2025
PRIMARY
PUBCHEM
169490902
Created by admin on Wed Apr 02 18:47:27 GMT 2025 , Edited by admin on Wed Apr 02 18:47:27 GMT 2025
PRIMARY
NIH
NCATS
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