Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C4H9NO2Se |
| Molecular Weight | 182.08 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[Se]C[C@H](N)C(O)=O
InChI
InChIKey=XDSSPSLGNGIIHP-VKHMYHEASA-N
InChI=1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
| Molecular Formula | C4H9NO2Se |
| Molecular Weight | 182.08 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Methylselenocysteine is a part of the mammalian physiology and is a well-tolerated, versatile and economical antiangiogenic agent. This compound participated in clinical trial to determine if vitamin supplementation with this compound could restore disruption of circadian rhythm in shift workers. The preclinical efficacy of methylselenocysteine has shown the combination of methylselenocysteine with androgen deprivation therapy can be useful for the treatment of advanced prostate cancer.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Methylselenocysteine preventing castration-resistant progression of prostate cancer. | 2015-06-15 |
|
| Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression. | 2004-07 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:12:37 GMT 2025
by
admin
on
Mon Mar 31 18:12:37 GMT 2025
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| Record UNII |
TWK220499Z
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| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C73539
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NCI_THESAURUS |
C275
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admin on Mon Mar 31 18:12:37 GMT 2025 , Edited by admin on Mon Mar 31 18:12:37 GMT 2025
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DSLD |
3204 (Number of products:2)
Created by
admin on Mon Mar 31 18:12:37 GMT 2025 , Edited by admin on Mon Mar 31 18:12:37 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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9068
Created by
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C63678
Created by
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TWK220499Z
Created by
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147004
Created by
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DTXSID801020160
Created by
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PRIMARY | |||
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27812
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SUB193912
Created by
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Methylselenocysteine
Created by
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26046-90-2
Created by
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100000178275
Created by
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DB12697
Created by
admin on Mon Mar 31 18:12:37 GMT 2025 , Edited by admin on Mon Mar 31 18:12:37 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
