NEONATAL FC RECEPTOR

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:27:36 GMT 2025` Edited by `admin` on `Wed Apr 02 04:27:36 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	FC BINDING PROTEIN
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	TW3XAW0RCY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FCRN

Preferred Name

English

NEONATAL FC RECEPTOR

Common Name

English

IGG RECEPTOR FCRN LARGE SUBUNIT P51

Common Name

English

IGG FC FRAGMENT RECEPTOR TRANSPORTER ALPHA CHAIN

Common Name

English

Code System Code Type Description

UNIPROT

P55899

Created by admin on Wed Apr 02 04:27:36 GMT 2025 , Edited by admin on Wed Apr 02 04:27:36 GMT 2025

PRIMARY

FDA UNII

TW3XAW0RCY

Created by admin on Wed Apr 02 04:27:36 GMT 2025 , Edited by admin on Wed Apr 02 04:27:36 GMT 2025

PRIMARY

From	To
2_25	2_80
1_96	1_159
1_198	1_252

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_102

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Comments:

An antibody fragment that binds to the neonatal Fc receptor (FcRn), preventing FcRn from recycling immunoglobulin G (IgG) back into the blood.[2] The medication causes a reduction in overall levels of IgG, including the abnormal acetylcholine receptor (AChR) antibodies that are present in myasthenia gravis.

Amount: