EFOCIPEGTRUTIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:17:34 GMT 2023` Edited by `admin` on `Sat Dec 16 14:17:34 GMT 2023`
Protein Type	PEPTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	TUI1MDD9F6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EFOCIPEGTRUTIDE

Official Name

English

IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE), 1-ETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOPROPYL)AMINO)PROPYL)-.OMEGA.-HYDROXYPOLY(OXY-1,2-ETHANEDIYL), THIOETHE

Systematic Name

English

HM15211 (LONG-ACTING GLP-1/GIP/GLUCAGON TRIPLE AGONIST)

Common Name

English

GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT

Common Name

English

efocipegtrutide [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

620717

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

FDA ORPHAN DRUG

728019

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

FDA ORPHAN DRUG

727919

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

FDA ORPHAN DRUG

815521

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

Code System Code Type Description

INN

12007

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

PRIMARY

CAS

2513399-19-2

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

PRIMARY

FDA UNII

TUI1MDD9F6

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

PRIMARY

NCI_THESAURUS

C188633

Created by admin on Sat Dec 16 14:17:34 GMT 2023 , Edited by admin on Sat Dec 16 14:17:34 GMT 2023

PRIMARY

From	To
1_3	2_3
1_35	1_95
1_141	1_199
2_35	2_95
2_141	2_199

Linkage Type	Residue Index
AMIDE BOND	3_16	3_20
CYS-LINKER-N-TERMINAL	1_1	3_40

Related Record Type Details


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> AGONIST

Amount:


					G2BWF9H576

GLUCAGON RECEPTOR

TARGET -> AGONIST

Amount:


					D6H00MV7K8

GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					TUI1MDD9F6

EFOCIPEGTRUTIDE

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL