Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Mon Mar 31 22:27:59 GMT 2025
by
admin
on
Mon Mar 31 22:27:59 GMT 2025
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| Source Materials Class | ORGANISM |
| Source Materials Type | PROTIST |
| Source Materials State | LIVE |
| Organism Family | Trypanosomatidae |
| Organism Genus | Leishmania |
| Organism Species | donovani |
| Author | LAVERAN ET MESNIL |
| Part | whole |
| Record UNII |
TT13N8250S
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English | ||
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Preferred Name | English |
| Code System | Code | Type | Description | ||
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TT13N8250S
Created by
admin on Mon Mar 31 22:27:59 GMT 2025 , Edited by admin on Mon Mar 31 22:27:59 GMT 2025
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PRIMARY | |||
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5661
Created by
admin on Mon Mar 31 22:27:59 GMT 2025 , Edited by admin on Mon Mar 31 22:27:59 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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VACCINE ANTIGEN->TARGET ORGANISM | |||
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INHIBITOR->TARGET ORGANISM |
antiprotozoal; selective inhibitor of the kinetoplastid proteasome
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR->TARGET ORGANISM |
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INHIBITOR -> TARGET |
Dosing at 1 mg/kg b.i.d. led to a 95% reduction of parasite burden in the liver, an efficacy equivalent to that effected by a 12 mg/kg q.d. regimen of miltefosine.
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