Avacincaptad Pegol

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 11:58:31 GMT 2023` Edited by `admin` on `Sat Dec 16 11:58:31 GMT 2023`
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	TT0V5JLG5B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Avacincaptad Pegol

Official Name

English

Zimura

Brand Name

English

avacincaptad pegol [INN]

Common Name

English

Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, 5′-ether with RNA ((2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-G-(2′-deoxy-2′-fluoro)C-Gm-Gm-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-f

Common Name

English

ARC-1905 Free Acid

Code

English

Avacincaptad pegol [WHO-DD]

Common Name

English

Code System Code Type Description

INN

10099

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

PRIMARY

SMS_ID

300000036963

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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DAILYMED

TT0V5JLG5B

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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DRUG BANK

DB15165

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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NCI_THESAURUS

C171668

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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CAS

1613641-69-2

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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FDA UNII

TT0V5JLG5B

Created by admin on Sat Dec 16 11:58:32 GMT 2023 , Edited by admin on Sat Dec 16 11:58:32 GMT 2023

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Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_39	1 / 39
L-Ribose	1_5;1_17;1_32	3 / 39
2'-O-Methyl-Ribose	1_2;1_7-1_8;1_13-1_15;1_20-1_22;1_26-1_28;1_36;1_38	14 / 39
2'-Fluoro-Ribose	1_1;1_3-1_4;1_6;1_9-1_12;1_16;1_18-1_19;1_23-1_25;1_29-1_31;1_33-1_35;1_37	21 / 39

Linkage	Site Range	Site Count
Phosphate	1_2-1_39	38 / 38

Related Record Type Details


					K86ENL12I5

Avacincaptad Pegol Sodium

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					TT0V5JLG5B

Avacincaptad Pegol

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS			AVACINCAPTAD PEGOL 5'-MODIFICATION	XIH22S8L8T
3'-3' LINKER	[1_39]	SITE_SPECIFIC			THYMIDINE 3'-MONOPHOSPHATE	Q84LAH3NDH

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER	CHEMICAL