PABINAFUSP ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:05:30 GMT 2025` Edited by `admin` on `Wed Apr 02 01:05:30 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY FUSION PROTEIN
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	TRF8S0U6ON
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PABINAFUSP ALFA

Official Name

English

JR-141

Preferred Name

English

JR141

Code

English

pabinafusp alfa [INN]

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN TRANSFERRIN RECEPTOR 1, TFR1) HUMANIZED MONOCLONAL ANTIBODY, FUSED WITH HUMAN IDURONATE-2-SULFATASE, GLYCOFORM ALFA:

Common Name

English

Pabinafusp alfa [WHO-DD]

Common Name

English

PABINAFUSP ALFA [JAN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN TRANSFERRIN RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JR-141 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE, DISULFIDE WITH HUMAN-MUS MUSCULUS MONO

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

652518

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

Code System Code Type Description

INN

10995

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

FDA UNII

TRF8S0U6ON

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

DRUG BANK

DB15633

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

CAS

2140211-48-7

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

SMS_ID

100000177993

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

NCI_THESAURUS

C170281

Created by admin on Wed Apr 02 01:05:30 GMT 2025 , Edited by admin on Wed Apr 02 01:05:30 GMT 2025

PRIMARY

From	To
1_22	1_96
1_145	1_201
1_221	3_219
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426
2_22	2_96
2_145	2_201
2_262	2_322
2_368	2_426
1_596	1_609
1_847	1_857
2_596	2_609
2_847	2_857
2_221	4_219
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199

Glycosylation Link Type	Site
N	1_298
N	1_456
N	1_540
N	1_569
N	1_671
N	1_705
N	1_750
N	1_938
N	1_962
N	2_298
N	2_456
N	2_540
N	2_569
N	2_671
N	2_705
N	2_750
N	2_938
N	2_962

Related Record Type Details


					5W8JGG2651

TARGET->ENZYME REPLACEMENT

Amount:

Related Record Type Details


					TRF8S0U6ON

PABINAFUSP ALFA

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL