LOMEVACTONE

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NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H17ClO2
Molecular Weight	300.779
Optical Activity	( + / - )
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LOMEVACTONE

Structure Search

SMILES

C[C@@H]1C[C@H]([C@@H](C(=O)O1)C2=CC=CC=C2)C3=CC=C(Cl)C=C3

InChI

InChIKey=QSAFSJAOPPHPTK-DQYPLSBCSA-N

InChI=1S/C18H17ClO2/c1-12-11-16(13-7-9-15(19)10-8-13)17(18(20)21-12)14-5-3-2-4-6-14/h2-10,12,16-17H,11H2,1H3/t12-,16+,17+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C18H17ClO2
Molecular Weight	300.779
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6136063 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 739, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Lomevactone is a psychostimulant and antidepressant drug

Approval Year

PubMed

PubMed

Title	Date	PubMed
The progressive ratio schedule as a model for studying the psychomotor stimulant activity of drugs in the rat.	1983	6136063

Sample Use Guides

In Vivo Use Guide

2 or 4 mg/kg

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:42 UTC 2023` Edited by `admin` on `Fri Dec 15 16:11:42 UTC 2023`
Record UNII	TP71SPS85C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LOMEVACTONE

Official Name

English

lomevactone [INN]

Common Name

English

4-(P-CHLOROPHENYL)TETRAHYDRO-6-METHYL-3-PHENYL-2H-PYRAN-2-ONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

Code System Code Type Description

PUBCHEM

11758301

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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EPA CompTox

DTXSID601024659

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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SMS_ID

100000082023

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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EVMPD

SUB08565MIG

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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ChEMBL

CHEMBL2105202

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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CAS

81478-25-3

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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INN

5249

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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NCI_THESAURUS

C81491

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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FDA UNII

TP71SPS85C

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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WIKIPEDIA

Lomevactone

Created by admin on Fri Dec 15 16:11:42 UTC 2023 , Edited by admin on Fri Dec 15 16:11:42 UTC 2023

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Related Record Type Details


					TP71SPS85C

ACTIVE MOIETY