INTERFERON ALPHA/BETA RECEPTOR 2

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	TP3WG3U0B5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INTERFERON ALPHA/BETA RECEPTOR 2

Common Name

English

IFNARB

Common Name

English

IFNABR

Common Name

English

IFN-R-2

Common Name

English

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Code System

Code

Type

Description

UNIPROT

P48551

PRIMARY

FDA UNII

TP3WG3U0B5

PRIMARY

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Subunit 0

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From	To
1_13	1_96
1_59	1_67
1_181	1_201

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Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_32
N	1_61
N	1_90
N	1_162
N	1_166

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Related Record

Type

Details


					G8RGG88B68

PEGINTERFERON ALFA-2B

AGONIST -> TARGET


					H9CK7SS0T6

NOVAFERON

AGONIST -> TARGET

Comments:

Nova exhibited a higher binding affinity for IFN receptor 2 (IFNR2) than rhIFN-α2b, which is one of the possible reasons accounting for its stronger actions against tumor cells compared with rhIFN-α2b.

Interaction Type:

AGONIST

Qualification:

Kd

Amount:

0.0123 NANOMOLAR (average)


					N7FO1V18PR

ERAMKAFUSP ALFA

ACTIVATOR -> TARGET


					Q46947FE7K

PEGINTERFERON ALFA-2A

AGONIST -> TARGET


					695DKH33EI

NYLIDRIN

AGONIST -> TARGET

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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