U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:18:20 GMT 2023
Edited
by admin
on Sat Dec 16 14:18:20 GMT 2023
Protein Type PEPTIDE
Protein Sub Type
Sequence Type COMPLETE
Record UNII
TO3JYR3BOU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEGCETACOPLAN
INN   USAN  
Official Name English
SYFOVRE
Brand Name English
PEGCETACOPLAN [USAN]
Common Name English
POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-HYDRO-.OMEGA.-HYDROXY-, 15,15'-DIESTER WITH N-ACETYL-L-ISOLEUCYL-L-CYSTEINYL-L-VALYL-1-METHYL-L-TRYPTOPHYL-L-GLUTAMINYL-L-.ALPHA.-ASPARTYL-L-TRYPTOPHYLGLYCYL-L-ALANYL-L-HISTIDYL-L-ARGINYL-L-CYSTEINYL-L-THREONYL-2-(2-(2-A
Systematic Name English
pegcetacoplan [INN]
Common Name English
O,O'-BIS((S2,S12-CYCLO(N-ACETYL-L-ISOLEUCYL-L-CYSTEINYL-L-VALYL-1-METHYL-L-TRYPTOPHYL-L-GLUTAMINYL-L-.ALPHA.-ASPARTYL-L-TRYPTOPHYLGLYCYL-L-ALANYL-L-HISTIDYL-L-ARGINYL-L-CYSTEINYL-L-THREONYL-2-(2-(2-AMINOETHOXY)ETHOXY)ACETYL-L-LYSINAMIDE))-N6.15-CARBONYL)
Systematic Name English
EMPAVELI
Brand Name English
APL-2
Code English
Pegcetacoplan [WHO-DD]
Common Name English
PEGCETACOPLAN [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 427614
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
FDA ORPHAN DRUG 817321
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
FDA ORPHAN DRUG 627018
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
FDA ORPHAN DRUG 799620
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
FDA ORPHAN DRUG 633418
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
Code System Code Type Description
DAILYMED
TO3JYR3BOU
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
USAN
FG-216
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
WIKIPEDIA
Pegcetacoplan
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
INN
10743
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
EVMPD
SUB195466
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
NCI_THESAURUS
C121135
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
CAS
2019171-69-6
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
RXCUI
2557372
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
FDA UNII
TO3JYR3BOU
Created by admin on Sat Dec 16 14:18:20 GMT 2023 , Edited by admin on Sat Dec 16 14:18:20 GMT 2023
PRIMARY
From To
1_2 1_12
2_2 2_12
Related Record Type Details
TARGET -> INHIBITOR
Inhibits C3 activation
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL