| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H28N2O2 |
| Molecular Weight | 352.4699 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC1=CC=C(C=C1)C(=O)NN(C(=O)C2=CC(C)=CC(C)=C2)C(C)(C)C
InChI
InChIKey=QYPNKSZPJQQLRK-UHFFFAOYSA-N
InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)
| Molecular Formula | C22H28N2O2 |
| Molecular Weight | 352.4699 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Tebufenozide, a non-steroidal insect growth regulator, is extensively used to control pests. It is considered an environmentally friendly pesticide due to its specificity on target insects. However, some studies have found that tebufenozide is cytotoxic to man, although the exact mechanism is unknown. Experiments with human cells have shown that tebufenozide induced DNA damage in HeLa cells. This effect was achieved by inducing the cell cycle arrest and by apoptosis through activating the p53 protein in a Bax- and Bcl-2-triggered mitochondrial pathway.