U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:30:07 GMT 2023
Edited
by admin
on Sat Dec 16 13:30:07 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
TN8CEX4UT2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MODAKAFUSP ALFA
USAN   INN  
Official Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (EC:3.2.2.6) (ADPRC 1/CADRP HYDROLASE 1, CELL SURFACE ANTIGEN CD38)), HUMANIZED MONOCLONAL ANTIBODY, FUSED AT EACH C-TERMINUS OF THE HEAVY CHAINS (1-447, 1''-447'') TO
Common Name English
modakafusp alfa [INN]
Common Name English
IMMUNOGLOBULIN G4 (228-PROLINE), ANTI-(HUMAN ANTIGEN CD38) (HUMAN-RATTUS NORVEGICUS MONOCLONAL TAK-573 .GAMMA.4-CHAIN) FC C-TERMINAL FUSION PROTEIN WITH HUMAN INTERFERON .ALPHA.2B (106-ALANINE,145-ASPARTIC ACID), DISULFIDE WITH HUMAN-RATTUS NORVEGICUS MO
Systematic Name English
TAK573
Code English
ANTI-CD38-TARGETED IGG4-ATTENUATED IFNA TAK-573
Common Name English
TEV-48573
Code English
TAK-573
Code English
Modakafusp alfa [WHO-DD]
Common Name English
MODAKAFUSP ALFA [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129820
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
Code System Code Type Description
CAS
2254522-19-3
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
PRIMARY
FDA UNII
TN8CEX4UT2
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
PRIMARY
INN
11306
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
PRIMARY
NCI_THESAURUS
C140427
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
PRIMARY
USAN
JK-216
Created by admin on Sat Dec 16 13:30:07 GMT 2023 , Edited by admin on Sat Dec 16 13:30:07 GMT 2023
PRIMARY
From To
1_22 1_96
1_134 3_214
1_147 1_203
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
2_22 2_96
2_134 4_214
2_147 2_203
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_448 1_545
1_476 1_585
2_448 2_545
2_476 2_585
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL