Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H21ClN4.2ClH |
Molecular Weight | 377.74 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.CC1=CC(CCN2CCN(CC2)C3=CC=CC(Cl)=C3)=NN1
InChI
InChIKey=FOZDCFRVHJVSIY-UHFFFAOYSA-N
InChI=1S/C16H21ClN4.2ClH/c1-13-11-15(19-18-13)5-6-20-7-9-21(10-8-20)16-4-2-3-14(17)12-16;;/h2-4,11-12H,5-10H2,1H3,(H,18,19);2*1H
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C16H21ClN4 |
Molecular Weight | 304.818 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
CNS Activity
Originator
Sources: https://patents.google.com/patent/US3491097
Curator's Comment: reference retrieved from https://www.drugfuture.com/chemdata/mepiprazole.html
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Clinical trial of 3-methyl-5-(beta-N'-(N-m-chlorophenylpiperazino)ethyl)-pyrazole dihydrochloride (Mepiprazol) in the therapy of psychovegetative disorders. | 1975 |
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[A controlled double-blind crossover study of the efficacy of mepiprazol (EMD 16.923) and of diazepam in the treatment of neurotic disorders]. | 1975 May |
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[Psychopharmological research with EMD 16-923 in patients with different degrees of anxiety]. | 1976 |
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Mepiprazole, a new psychotropic drug: effects on uptake and retention of monoamines in rat brain synaptosomes. | 1976 Aug 17 |
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The effect of mepiprazole on central monoamine neurons. Evidence for increased 5-hydroxytryptamine and dopamine receptor activity. | 1976 Jan |
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1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole. | 1982 Oct |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 06:01:43 UTC 2023
by
admin
on
Sat Dec 16 06:01:43 UTC 2023
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Record UNII |
TN5WJ92YGP
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Record Status |
Validated (UNII)
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Record Version |
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DTXSID80942499
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DBSALT001263
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20344-15-4
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m306
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TN5WJ92YGP
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209757
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |