BURIMAMIDE

Investigational

CNC(=S)NCCCCC1=CN=CN1

InChIKey=HXRBAVXGYZUSED-UHFFFAOYSA-N

InChI=1S/C9H16N4S/c1-10-9(14)12-5-3-2-4-8-6-11-7-13-8/h6-7H,2-5H2,1H3,(H,11,13)(H2,10,12,14)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice.	1994 Jun	7976808
Constitutive activity and structural instability of the wild-type human H2 receptor.	1998 Aug	9681472
Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.	2001 Dec	11714875
Central endogenous histamine modulates sympathetic outflow through H3 receptors in the conscious rabbit.	2003 Jul	12839877
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.	2008 Jun 6	18538007
Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra.	2008 Nov	18761715
The chemical basis of pharmacology.	2010 Dec 7	21058655
The effect of intracerebroventricular injection of histamine in visceral nociception induced by acetic acid in rats.	2010 Oct	21206620

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:58:24 GMT 2023` Edited by `admin` on `Fri Dec 15 17:58:24 GMT 2023`
Record UNII	TN5A4OD2TV
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BURIMAMIDE

Common Name

English

N-METHYL-N'-(4-(4(5)-IMIDAZOLYL)BUTYL)THIOUREA

Common Name

English

N-METHYL-N'-(4(5)-IMIDAZOLYLBUTYL)THIOUREA

Common Name

English

THIOUREA, N-(4-(1H-IMIDAZOL-4-YL)BUTYL)-N'-METHYL-

Systematic Name

English

THIOUREA, N-(4-(1H-IMIDAZOL-5-YL)BUTYL)-N'-METHYL-

Systematic Name

English

N-(4-IMIDAZOL-4-YLBUTYL)-N'-METHYLTHIOUREA

Systematic Name

English

Code System Code Type Description

PUBCHEM

3032915