BURIMAMIDE

Investigational

CNC(=S)NCCCCC1=CN=CN1

InChIKey=HXRBAVXGYZUSED-UHFFFAOYSA-N

InChI=1S/C9H16N4S/c1-10-9(14)12-5-3-2-4-8-6-11-7-13-8/h6-7H,2-5H2,1H3,(H,11,13)(H2,10,12,14)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
The chemical basis of pharmacology.	2010-12-07	21058655
The effect of intracerebroventricular injection of histamine in visceral nociception induced by acetic acid in rats.	2010-10	21206620
Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra.	2008-11	18761715
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.	2008-06-06	18538007
Central endogenous histamine modulates sympathetic outflow through H3 receptors in the conscious rabbit.	2003-07	12839877
Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.	2001-12	11714875
Constitutive activity and structural instability of the wild-type human H2 receptor.	1998-08	9681472
Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice.	1994-06	7976808

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:58:18 GMT 2025` Edited by `admin` on `Mon Mar 31 18:58:18 GMT 2025`
Record UNII	TN5A4OD2TV
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

N-METHYL-N'-(4(5)-IMIDAZOLYLBUTYL)THIOUREA

Preferred Name

English

BURIMAMIDE

Common Name

English

N-METHYL-N'-(4-(4(5)-IMIDAZOLYL)BUTYL)THIOUREA

Common Name

English

THIOUREA, N-(4-(1H-IMIDAZOL-4-YL)BUTYL)-N'-METHYL-

Systematic Name

English

THIOUREA, N-(4-(1H-IMIDAZOL-5-YL)BUTYL)-N'-METHYL-

Systematic Name

English

N-(4-IMIDAZOL-4-YLBUTYL)-N'-METHYLTHIOUREA

Systematic Name

English

Code System Code Type Description

PUBCHEM

3032915