TENOFOVIR DISOPROXIL (S)-ENANTIOMER

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H30N5O10P
Molecular Weight	519.4428
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TENOFOVIR DISOPROXIL (S)-ENANTIOMER

Structure Search

SMILES

CC(C)OC(=O)OCOP(=O)(CO[C@@H](C)CN1C=NC2=C(N)N=CN=C12)OCOC(=O)OC(C)C

InChI

InChIKey=JFVZFKDSXNQEJW-AWEZNQCLSA-N

InChI=1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H30N5O10P
Molecular Weight	519.4428
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:26:11 GMT 2025` Edited by `admin` on `Wed Apr 02 08:26:11 GMT 2025`
Record UNII	TLO785XZL3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TENOFOVIR DISOPROXIL (S)-ENANTIOMER

Common Name

English

BIS(1-METHYLETHYL) 5-(((1S)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL)-5-OXO-2,4,6,8-TETRAOXA-5-.LAMBDA.5-PHOSPHANONANEDIOATE [WHO-IP]

Preferred Name

English

TENOFOVIR DISOPROXIL FUMARATE IMPURITY G [WHO-IP]

Common Name

English

2,4,6,8-TETRAOXA-5-PHOSPHANONANEDIOIC ACID, 5-(((1S)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL)-, 1,9-BIS(1-METHYLETHYL) ESTER, 5-OXIDE

Systematic Name

English

Code System Code Type Description

CAS

1280130-08-6

Created by admin on Wed Apr 02 08:26:11 GMT 2025 , Edited by admin on Wed Apr 02 08:26:11 GMT 2025

PRIMARY

PUBCHEM

119830

Created by admin on Wed Apr 02 08:26:11 GMT 2025 , Edited by admin on Wed Apr 02 08:26:11 GMT 2025

PRIMARY

FDA UNII

TLO785XZL3

Created by admin on Wed Apr 02 08:26:11 GMT 2025 , Edited by admin on Wed Apr 02 08:26:11 GMT 2025

PRIMARY

Related Record Type Details


					OTT9J7900I

TENOFOVIR DISOPROXIL FUMARATE

PARENT -> IMPURITY

Comments:

The production method is validated to ensure that the substance, if tested, would comply with: ? a limit of not more than 1.0% for the tenofovir disoproxil (S)-enantiomer (impurity G) using a suitable chiral chromatographic method.

Amount: