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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H30N5O10P
Molecular Weight 519.4435
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TENOFOVIR DISOPROXIL (S)-ENANTIOMER

SMILES

CC(C)OC(=O)OCOP(=O)(CO[C@@]([H])(C)Cn1cnc2c(N)ncnc21)OCOC(=O)OC(C)C

InChI

InChIKey=JFVZFKDSXNQEJW-AWEZNQCLSA-N
InChI=1S/C19H30N5O10P/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22)/t14-/m0/s1

HIDE SMILES / InChI

Molecular Formula C19H30N5O10P
Molecular Weight 519.4435
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Fri Jun 25 20:45:04 UTC 2021
Edited
by admin
on Fri Jun 25 20:45:04 UTC 2021
Record UNII
TLO785XZL3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TENOFOVIR DISOPROXIL (S)-ENANTIOMER
Common Name English
TENOFOVIR DISOPROXIL FUMARATE IMPURITY G [WHO-IP]
Common Name English
BIS(1-METHYLETHYL) 5-(((1S)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL)-5-OXO-2,4,6,8-TETRAOXA-5-.LAMBDA.5-PHOSPHANONANEDIOATE [WHO-IP]
Common Name English
2,4,6,8-TETRAOXA-5-PHOSPHANONANEDIOIC ACID, 5-(((1S)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL)-, 1,9-BIS(1-METHYLETHYL) ESTER, 5-OXIDE
Systematic Name English
Code System Code Type Description
CAS
1280130-08-6
Created by admin on Fri Jun 25 20:45:04 UTC 2021 , Edited by admin on Fri Jun 25 20:45:04 UTC 2021
PRIMARY
PUBCHEM
119830
Created by admin on Fri Jun 25 20:45:04 UTC 2021 , Edited by admin on Fri Jun 25 20:45:04 UTC 2021
PRIMARY
FDA UNII
TLO785XZL3
Created by admin on Fri Jun 25 20:45:04 UTC 2021 , Edited by admin on Fri Jun 25 20:45:04 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
The production method is validated to ensure that the substance, if tested, would comply with: ? a limit of not more than 1.0% for the tenofovir disoproxil (S)-enantiomer (impurity G) using a suitable chiral chromatographic method.