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METRELEPTIN
TL60C27RLH
US Approved Rx (2014)
First approved in 2014
General
Record Details
Names
13
Classification
5
Identifiers
18
Subunits
1
Active Moiety
1
Characteristic Attributes
2
METRELEPTIN
TL60C27RLH
US Approved Rx (2014)
First approved in 2014
General
Approval Year
2014
494
Record Details
Substance Class
Protein
Protein Type
HORMONE
Protein Sub Type
Other|LEPTIN
Sequence Origin
HUMAN
Sequence Type
COMPLETE
Record UNII
TL60C27RLH
Record Status
Validated (UNII)
Record Version
27
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Names
13
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entries
Name
Type
Language
Name
Type
Language
METRELEPTIN
Official Name
English
R-METHULEPTIN
Common Name
English
metreleptin [INN]
Common Name
English
N-METHIONYLLEPTIN (HUMAN)
Common Name
English
METRELEPTIN [USAN]
Common Name
English
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1
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Classification
5
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Established Pharmacologic Class
Established Pharmacologic Class
[EPC]
Leptin Analog
[EPC]
NDF-RT
N0000190854
Positive
EU ORPHAN DRUG
Positive
Treatment of familial partial lipodystrophy
EU-Orphan Drug
EU/3/12/1022
Amino acids and derivatives
ATC
ALIMENTARY TRACT AND METABOLISM
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Amino acids and derivatives
metreleptin
WHO-ATC
A16AA07
Designated
ORPHAN DRUG
Designated
Treatment of leptin deficiency secondary to generalized lipodystrophy and partial familial lipodystrophy
FDA ORPHAN DRUG
144301
Designated/Approved
ORPHAN DRUG
Designated/Approved
Treatment of metabolic disorders secondary to lipodystrophy
FDA ORPHAN DRUG
146701
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Identifiers
18
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Code System
Code
Type
Description
Code System
Code
Type
Description
JAPANESE REVIEW
METRELEPTIN
PRIMARY
APPROVED MARCH 2013
DRUG CENTRAL
4826
PRIMARY
CAS
186018-45-1
PRIMARY
IUPHAR
7333
PRIMARY
NDF-RT
N0000175452
PRIMARY
Analogs/Derivatives [Chemical/Ingredient]
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Subunits
1
Subunit 0
>SUBUNIT_0
Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
TL60C27RLH
METRELEPTIN
ACTIVE MOIETY
Amount:
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C714H1165N191O221S6
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 16200 Da (average)
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