Abiprubart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:18:07 GMT 2023` Edited by `admin` on `Sat Dec 16 15:18:07 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	TIN30KQI3W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Abiprubart

Official Name

English

Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L

Common Name

English

Immunoglobulin G4 [222-proline], anti-(human CD40 antigen) (human-Mus musculus monoclonal KPL-404 γ4-chain), disulfide with human-Mus musculus monoclonal KPL-404 κ-chain, dimer

Common Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibody

Common Name

English

abiprubart [INN]

Common Name

English

Code System Code Type Description

CAS

2765071-95-0

Created by admin on Sat Dec 16 15:18:07 GMT 2023 , Edited by admin on Sat Dec 16 15:18:07 GMT 2023

PRIMARY

INN

12636

Created by admin on Sat Dec 16 15:18:07 GMT 2023 , Edited by admin on Sat Dec 16 15:18:07 GMT 2023

PRIMARY

FDA UNII

TIN30KQI3W

Created by admin on Sat Dec 16 15:18:07 GMT 2023 , Edited by admin on Sat Dec 16 15:18:07 GMT 2023

PRIMARY

From	To
1_22	1_96
1_128	3_213
1_141	1_197
1_220	2_220
1_223	2_223
1_255	1_315
1_361	1_419
2_22	2_96
2_128	4_213
2_141	2_197
2_255	2_315
2_361	2_419
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_291
N	2_291

Related Record Type Details


					CA9PO31PIJ

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					TIN30KQI3W

Abiprubart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL