PERISOXAL CITRATE

Details

Stereochemistry	RACEMIC
Molecular Formula	2C16H20N2O2.C6H8O7
Molecular Weight	736.8079
Optical Activity	( + / - )
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.OC(CN1CCCCC1)C2=NOC(=C2)C3=CC=CC=C3.OC(CN4CCCCC4)C5=NOC(=C5)C6=CC=CC=C6

InChI

InChIKey=OOSOWXQJLLTIAF-UHFFFAOYSA-N

InChI=1S/2C16H20N2O2.C6H8O7/c2*19-15(12-18-9-5-2-6-10-18)14-11-16(20-17-14)13-7-3-1-4-8-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h2*1,3-4,7-8,11,15,19H,2,5-6,9-10,12H2;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C6H8O7
Molecular Weight	192.1235
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C16H20N2O2
Molecular Weight	272.3422
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.ncbi.nlm.nih.gov/pubmed/6489869
Curator's Comment: Description was created based on several sources, including http://www.drugfuture.com/chemdata/perisoxal.html

Perisoxal citrate is a basic nonsteroidal anti-inflammatory and analgesic drug.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: http://www.ncbi.nlm.nih.gov/pubmed/397126	Palliative		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[Clinical trial of a new non-steroidal anti-inflammatory analgesic, 31252-S, for postoperative pain following tooth extraction and minor ambulatory surgery].	1979	397126
Absorption, excretion, distribution and metabolism of perisoxal in rats.	1979 May	315279
Determination of perisoxal and its phenolic metabolites in rat, rabbit and human urine.	1980 Jul	7448957

Patents

Sample Use Guides

In Vivo Use Guide

200 mg/man, p. o

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:54:31 GMT 2023` Edited by `admin` on `Sat Dec 16 04:54:31 GMT 2023`
Record UNII	THV8Y61BB4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PERISOXAL CITRATE

Common Name

English

Perisoxal citrate [WHO-DD]

Common Name

English

1-PIPERIDINEETHANOL, .ALPHA.-(5-PHENYL-3-ISOXAZOLYL)-, CITRATE (2:1)

Common Name

English

PERISOXAL CITRATE [MI]

Common Name

English

S-31252

Code

English

PERISOXAL CITRATE [JAN]

Common Name

English

1-PIPERIDINEETHANOL, .ALPHA.-(5-PHENYL-3-ISOXAZOLYL)-, CITRATE

Systematic Name

English

(±)-PERISOXAL CITRATE

Common Name

English

1-PIPERIDINEETHANOL, .ALPHA.-(5-PHENYL-3-ISOXAZOLYL)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (2:1)

Common Name

English

ISOXAL

Brand Name

English

Code System Code Type Description

ChEMBL

CHEMBL2105453